A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Gene Dmel\wy

General Information
SymbolDmel\wySpeciesD. melanogaster
NamewavyAnnotation symbol
Feature typegeneFlyBase IDFBgn0004031
Created / Updated2006-08-22/2006-08-22
Genomic Location
Chromosome (arm)Recombination map1-40.7
Cytogenetic map11D9-11D10Sequence location
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Automatically generated summary

See sections below for more information
The gene wavy is referred to in FlyBase by the symbol wy (FBgn0004031). It has the cytological map location 11D9-11D10. It has not been localized to the genome sequence. Its molecular function is unknown. The biological processes in which it is involved are not known. 7 alleles are reported. The phenotypes of these alleles are annotated with: wing; abdomen; wing vein L1. It has no annotated transcripts.

hide Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage
wy: wavy
thumb
wy: wavy
From Nachtsheim, 1928, Z. Indukt. Abstamm. Vererbungsl. 48: 245-58.
Wings transversely waved, usually turned up at tip. Abdomen long and narrow. Marginal vein kinked even when other characters overlap wild type. RK2.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
11D9-11D10  
Left limit from recombination mapping relative to sno (FBrf0023568) Right limit from non-inclusion within Dp(1;4)r+l (FBrf0045066)  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
1-40.7
 
Left of (cM)
Right of (cM)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
In direction of increasing cytology: sno? wy?
(Majumdar et al., 1995)
Gene Order (overall orientation not stated)
References
hide Gene Model & Products
Comments on Gene Model
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Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
Additional Polypeptide Data & Comments
Reported size (kD)
Comments
External Data
Linkouts
Crossreferences
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Maps to
      Does NOT map to
      Identified with
      hide Mapped Features & Mutations
      Type
      Symbol & Location
      Additional Notes
      References
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      Linkouts
      Crossreferences
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      FlyBase-Curated Data
      Transcript and
      Protein data       		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
      hide Summary of Transcript Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
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        Stage
        Tissue/Position
        Reference
        Marker for
          Subcellular Localization
          CV Term
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          Linkouts
          FLIGHT - Cell culture data for RNAi and other high-throughput technologies
          •
          hide Alleles & Phenotypes
          hide Summary of Allele Phenotypes
          Lethality
          Allele
          viable
          lethal | male
          Other Phenotypes
          Allele
          visible
          Sterility
          Allele
          fertile
          Phenotype manifest in
          Allele
          wing
          abdomen
          wing vein L1
          hide Classical Alleles ( 7 )
          For All Classical Alleles Show

          Allele of wyClassMutagenStocksKnown lesion
          wy17 --
          wy274-20 --
          wy2
            		2 --
            wy40a0 --
            wy74i9 --
            wyP0 --
            wyspn0 --
            hide Alleles Carried on Transgenic Constructs ( 0 )
            For All Alleles Carried on Transgenic Constructs Show

            Allele of wyClassMutagenStocksKnown lesion
            hide Aneuploid Aberrations
            Useful deficiency
               
            Disrupted in
            (Craymer and Roy, 1980, Deak et al., 1982)
            (Lefevre and Peterson, 1972, Craymer and Roy, 1980, Deak et al., 1982)
            Not disrupted in
            (Craymer and Roy, 1980)
            (Deak et al., 1982)
            Not duplicated in
            (Schalet, 1986)
            (Schalet, 1986)
            Duplicated in
            (Brower et al., 1995)
            hide Transgenic Constructs & Insertions
            Transgenic Constructs
            Type of construct
            Name
            Expression data
            Insertions
            Type of insertions
            Name
            Expression data
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            Please look at the allele reports for the complete phenotype data
            hide Gene Ontology: Function, Process & Cellular Component ( 0 )
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            CV term
            Evidence
            References
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            CV term
            Evidence
            References
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            CV term
            Evidence
            References
            hide Sequence Ontology: Class of Gene
            gene
             
            hide Interactions & Pathways
            hide Summary of Genetic Interactions
            Interacts with
            Please look at the allele data for full details of the genetic interactions
            wy allele
            Gene
            References
            hide External Data
            Linkouts
            BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
            •
            hide Orthologs
            Genome-wide drosophilid orthologs
            Curated drosophilid orthologs
             
            Linkouts
            hide Functional Complementation between Species
            hide Inter-Species Misexpression Data
            Produces phenotype in
            Produces NO phenotype in
            hide Stocks & Reagents
            hide Stocks Listed in FlyBase ( 18 )
            Bloomington
            168
            wy1
            4451
            wch wy1/FM7c
            192
            y2 wy2 g2
            4355
            y1 Nfa-1 wy2 g2
            1162
            t1 v1 m74f wy74i
            1261
            y2 m74f wy74i sd1 oss
            1294
            t1 v1 m74f wy74i sd1 oss
            Kyoto
            105765
            wy1
            101223
            wch wy1
            101862
            wch wy1 ; cn1
            106233
            t1 v1 m74f wy74i
            106257
            y2 m74f wy74i sd1 oss
            hide Genomic Clones ( 0 )
            hide cDNA Clones ( 0 )
            cDNA Clones, Fully Sequenced
            BDGP DGC clones
            Other clones
            cDNA Clones, End Sequenced (ESTs)
            BDGP DGC clones
            Other clones
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            Affy Oligo
            Linkouts
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            Source for database identity of
            Source for database merge of
            Additional comments
            hide Comments About Role
            hide Comments About Molecular Function
            hide Other Comments
            hide External Crossreferences & Linkouts
            Sequence Crossreferences
            Other Crossreferences
            Linkouts
            BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions
            •
            FLIGHT - Cell culture data for RNAi and other high-throughput technologies
            •
            hide Synonyms & Secondary IDs ( 2 )
            Reported As
            Symbol Synonym
            wy
             
            Name Synonym
            wavy
             
            Secondary FlyBase IDs
              hide References ( 19 )
              Research paper
              Majumdar et al., 1997, Genes Dev. 11(10): 1341--1353
              strawberry notch encodes a conserved nuclear protein that functions downstream of Notch and regulates gene expression along the developing wing margin of Drosophila. [FBrf0093584]
              Brower et al., 1995, Development 121(5): 1311--1320
              Nonequivalent requirements for PS1 and PS2 integrin at cell attachments in Drosophila: genetic analysis of the a<down>PS1</down> integrin subunit. [FBrf0078125]
              Coyle-Thompson and Banerjee, 1993, Development 119(2): 377--395
              The strawberry notch gene functions with Notch in common developmental pathways. [FBrf0068459]
              Schalet, 1986, Mutat. Res. 163: 115--144
              The distribution of and complementation relationships between spontaneous X-linked recessive lethal mutations recovered from crossing long-term laboratory stocks of Drosophila melanogaster. [FBrf0045066]
              Deak et al., 1982, J. Embryol. exp. Morphol. 69: 61--81
              Mutations affecting the indirect flight muscles of Drosophila melanogaster. [FBrf0038305]
              Craymer, 1980, D. I. S. 55: 197--200
              [New mutants report.] [FBrf0063385]
              Craymer and Roy, 1980, D. I. S. 55: 200--204
              Report of New Mutants -- Drosophila melanogaster. [FBrf0034402]
              Waddle, 1977, D. I. S. 52: 3
              [New mutants report.] [FBrf0063947]
              Waddle, 1977, D. I. S. 52: 5
              Linkage data. [FBrf0063946]
              Lefevre and Peterson, 1972, D. I. S. 48: 126--127
              An unusual Notch mimic: glossy-like (g-l). [FBrf0023568]
              Bateman, 1950, D. I. S. 24: 54--56
              [New mutants report.] [FBrf0063295]
              John Innes Laboratory, 1941, D. I. S. 14: 39
              [New mutants report.] [FBrf0063550]
              Parker, 1935, D. I. S. 4: 62
              Locus of wy<up>2</up> (formerly cx<down>b</down>). [FBrf0003074]
              Patterson, 1932, Am. Nat. 66: 193--206
              Lethal mutations and deficiencies produced in the X-chromosome of Drosophila melanogaster by X-radiation. [FBrf0002302]
              Nachtsheim, 1928, Z. indukt. Abstamm.- u. VererbLehre 48: 245--258
              Beitrag zur Topographie des X-Chromosoms von Drosophila melanogaster. [FBrf0001760]
              Review
              Lefevre, 1976, Ashburner, Novitski, 1976 a: 31--66
              A photographic representation and interpretation of the polytene chromosomes of Drosophila melanogaster salivary glands. [FBrf0028326]
              Abstract
              Majumdar et al., 1995, A. Dros. Res. Conf. 36: 334B
              strawberry notch locus encodes a putative nuclear factor functioning in the Notch signaling pathway. [FBrf0078954]
              Book
              Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
              The Genome of Drosophila melanogaster. [FBrf0066905]
              Lindsley and Grell, 1968, Publs Carnegie Instn 627: 469pp
              Genetic variations of Drosophila melanogaster. [FBrf0020044]