Gene Dmel\Tre

General Information
Symbol	Dmel\Tre	Species	D. melanogaster
Name	Trehalose-sensitivity	Annotation symbol	CG15779
Feature type	protein_coding_gene	FlyBase ID	FBgn0003747
Created / Updated	2003-12-01/2003-12-01
Genomic Location
Chromosome (arm)	X	Recombination map	1-13.6
Cytogenetic map	5A12-5A12	Sequence location	X:5,574,760..5,576,476 [+]
Map ( GBrowse )
Summary Information
Automatically generated summary See sections below for more information	The gene Trehalose-sensitivity is referred to in FlyBase by the symbol Tre (CG15779, FBgn0003747). It has the cytological map location 5A12. Its sequence location is X:5574760..5576476. Its molecular function is described as: taste receptor activity; G-protein coupled receptor activity. It is involved in the biological processes: sensory perception of taste; sensory perception of sweet taste; detection of chemical stimulus involved in sensory perception of taste; G-protein coupled receptor protein signaling pathway. 71 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.
External Summaries

Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
Gene/Allele symbols may differ from current usage	Tre: Trehalose sensitivity (J.C. Hall) Locus determining differences in sensitivity to the taste of the disaccharide trehalose in behaviorly-based (fluid intake) tests (no differences in sensitivity to glucose, fructose, or sucrose). The Tre+ allele results in high trehalose sensitivity, the Tre allele in low trehalose sensitivity. Females with half the normal dose of a given Tre+ allele are half as sensitive to trehalose, but flies (male or female) with twice the normal dose of Tre+ show only a slight increase in sensitivity as compared to normal flies. Tre is thought to be a structural gene for the trehalose specific receptor in D. melanogaster (Tanimura et al., 1988).
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 5A12-5A12 Limits computationally determined from genome sequence between P{EP}Tre1^EP496 and P{EP}cv^EP1349&P{EP}CG32758^EP1368
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location	1-13.6 1- (Tanimura et al., 1982)
Left of (cM)	m (Tanimura et al., 1982)
Right of (cM)
Notes	Closely linked to cx. (Tanimura et al., 1982)
Molecular Map Data
Gene Order (in direction of increasing cytology) References Gene Order (overall orientation not stated) References
Gene Model & Products
Please see the GBrowse view of Dmel\Tre for information on other features
Comments on Gene Model

Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Tre-RA FBtr0070802 NM_078495 1335 444
Additional Transcript Data & Comments
Reported size (kB)	1.179 (longest cDNA) (Ishimoto et al., 2000)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kD) Length (aa) Theoretical pI RefSeq ID GenBank protein Tre-PA FBpp0070768 51.2 444 9.94 NP_511050 AAF46060
Additional Polypeptide Data & Comments
Reported size (kD)	392 (aa) (Ishimoto et al., 2000)
Comments
External Data
Linkouts	PANTHER - Protein classification by function, families, and pathways • FBgn0003747
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GPCR, rhodopsin-like (IPR000276) Trehalose receptor (IPR009318)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AB066610 AB066611 AB066612 AB066619 BAB68243 AB066620 BAB68244 AB066621 BAB68245 AB066622 BAB68246 AB066623 BAB68247 AB066624 BAB68248 AB066625 BAB68249 AB066626 BAB68250 AB066627 BAB68251 AB066628 BAB68252 AB066629 BAB68253 AB066630 BAB68254 AB066631 BAB68255 AB066632 BAB68256 AB066633 BAB68257 AB066634 BAB68258 AB066635 BAB68259 AB066636 BAB68260 AB066637 BAB68261 AB066638 BAB68262 AB066639 BAB68263 AB066640 BAB68264 AB066641 BAB68265 AB066642 BAB68266 AB066643 BAB68267 AB162449 BAD42667 AB162450 BAD42668 AB162451 BAD42669 AB162452 BAD42670 AB162453 BAD42671 AB162454 BAD42672 AB162455 BAD42673 AB162456 BAD42674 AB162457 BAD42675 AB162458 BAD42676 AB162459 BAD42677 AB162460 BAD42678 AB162461 BAD42679 AB162462 BAD42680 AB162463 BAD42681 AB162464 BAD42682 AB162465 BAD42683 AB162466 BAD42684 AB162467 BAD42685 AB162468 BAD42686 AB162469 BAD42687 AB162470 BAD42688 AB162471 BAD42689 AB162472 BAD42690 AB162473 BAD42691 AB162474 BAD42692 AB162475 BAD42693 AB162476 BAD42694 AB162477 BAD42695 AB162478 BAD42696 AB162479 BAD42697 AB162480 BAD42698 AB162481 BAD42699 AB162482 BAD42700 AB162483 BAD42701 AB162484 BAD42702 AB162485 BAD42703 AB162486 BAD42704 AB162487 BAD42705 AB162488 BAD42706 AB162489 BAD42707 AB162490 BAD42708 AB162491 BAD42709 AB162492 BAD42710 AB162493 BAD42711 AB162494 BAD42712 AB162495 BAD42713 AB162496 BAD42714 AB162497 BAD42715 AB162498 BAD42716 AB162499 BAD42717 AB162500 BAD42718 AB162501 BAD42719 AB162502 BAD42720 AB162503 BAD42721 AB162504 BAD42722 AB162505 BAD42723 AB162506 BAD42724 AB162507 BAD42725 AB162508 BAD42726 AB162509 BAD42727 AB162510 BAD42728 AB162511 BAD42729 AB162512 BAD42730 AB162513 BAD42731 AB162514 BAD42732 AB162515 BAD42733 AB162516 BAD42734 AB162517 BAD42735 AB162518 BAD42736 AB162519 BAD42737 AB162520 BAD42738 AB162521 BAD42739 AB162522 BAD42740 AB162523 BAD42741 AB162524 BAD42742 AB162525 BAD42743 AB162526 BAD42744 AB162527 BAD42745 AB162528 BAD42746 AB162529 BAD42747 AB162530 BAD42748 AB162531 BAD42749 AB162532 BAD42750 AB162533 BAD42751 AB162534 BAD42752 AB162535 BAD42753 AB162536 BAD42754 AB162537 BAD42755 AB162538 BAD42756 AB162539 BAD42757 AB162540 BAD42758 AB162541 BAD42759 AB162542 BAD42760 AB162543 BAD42761 AB162544 BAD42762 AB162545 BAD42763 AB162546 BAD42764 AB162547 BAD42765 AB162548 BAD42766 AB162549 BAD42767 AB162550 BAD42768 AB162551 BAD42769 AB162552 BAD42770 AB162553 BAD42771 AB162554 BAD42772 AB162555 BAD42773 AB162556 BAD42774 AB162557 BAD42775 AB162558 BAD42776 AB162559 BAD42777 AB162560 BAD42778 AB162561 BAD42779 AB162562 BAD42780 AB162563 BAD42781 AB162564 BAD42782 AB162565 BAD42783 AB162566 BAD42784 AB162567 BAD42785 AB162568 BAD42786 AB162569 BAD42787 AB162570 BAD42788 AB162571 BAD42789 AB162572 BAD42790 AB162573 BAD42791 AB162574 BAD42792 AB162575 BAD42793 AB162576 BAD42794 AB162577 BAD42795 AB162578 BAD42796 AB162579 BAD42797 AB162580 BAD42798 AB162581 BAD42799 AB162582 BAD42800 AB162583 BAD42801 AB162584 BAD42802 AB162585 BAD42803 AB162586 BAD42804 AB162587 BAD42805 AB162588 BAD42806 AB162589 BAD42807 AB162590 BAD42808 AB162591 BAD42809 AB162592 BAD42810 AB162593 BAD42811 AB162594 BAD42812 AB162595 BAD42813 AB162596 BAD42814 AB162597 BAD42815 AB162598 BAD42816