HomeGene Dmel\pnr
| General Information | ||||
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| Symbol | Dmel\pnr | Species | D. melanogaster | |
| Name | pannier | Annotation symbol | CG3978 | |
| Feature type | protein_coding_gene | FlyBase ID | FBgn0003117 | |
| Created / Updated | 2003-12-01/2003-12-01 | |||
| Genomic Location | ||||
| Chromosome (arm) | 3R | Recombination map | 3-58 | |
| Cytogenetic map | 89A13-89B1 | Sequence location | 3R:11,851,819..11,866,639 [+] | |
| Map ( GBrowse ) | 
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Summary Information
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Automatically generated summary
See sections below for more information | The gene pannier is referred to in FlyBase by the symbol pnr (CG3978, FBgn0003117). It has the cytological map location 89A13-89B1. Its sequence location is 3R:11851819..11866639. Its molecular function is described as: transcription factor activity; sequence-specific DNA binding; zinc ion binding. It is involved in the biological processes described with 20 unique terms, many of which group under: anatomical structure development; organ development; regulation of metabolic process; system development; regulation of biological process; transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; pigment metabolic process; embryonic pattern specification; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process. 55 alleles are reported. The phenotypes of these alleles are annotated with 50 unique terms, many of which group under: organ system; adult segment; peripheral nervous system; adult mesothoracic segment; nervous system; integumentary system; cuticle; portion of tissue; late extended germ band embryo; adult. It has 2 annotated transcripts and 2 annotated polypeptides. | |||
| External Summaries | ||||
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Phenotypic Description from the Red Book (Lindsley & Zimm 1992)
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| Gene/Allele symbols may differ from current usage | pnr: pannier
Homozygous lethal. Dorsal anterior of embryo open.
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Detailed Mapping Data
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| FlyBase Computed Cytological Location | ||||
Cytogenetic map Evidence for location 89A13-89B1
Limits computationally determined from genome sequence between P{PZ}blp01618 and P{PZ}gish04895&P{EP}EP3171
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| Experimentally Determined Cytological Location | ||||
Cytogenetic map Notes References 89A-89B (determined by in situ hybridisation)
89A-89A (determined by in situ hybridisation)
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| Experimentally Determined Recombination Data | ||||
| Location | 3-58.05 | |||
| Left of (cM) | ||||
| Right of (cM) | ||||
| Notes | ||||
| Molecular Map Data | ||||
Gene Order (in direction of increasing cytology)
References In direction of increasing cytology: pnr? Akt1- Sb? In direction of increasing cytology: pnr+ ird5- msps+ Akt1+ Gene Order (overall orientation not stated) References Overall orientation not stated: srp+ GATAe+ pnr+ | ||||
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Gene Model & Products
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Please see the
GBrowse view of
Dmel\pnr
for information on other features
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| Comments on Gene Model | ||||
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Transcript Data
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| Annotated Transcripts | ||||
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) | ||||
| Additional Transcript Data & Comments | ||||
| Reported size (kB) | 2.9 (compiled cDNA) 3.0 (northern blot) | |||
| Comments | ||||
| External Data | ||||
| Crossreferences | ||||
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Polypeptide Data
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| Annotated Polypeptides | ||||
Name FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
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| Additional Polypeptide Data & Comments | ||||
| Reported size (kD) | 540 (aa); 57 (kD) | |||
| Comments | ||||
| External Data | ||||
| Linkouts | PANTHER
- Protein classification by function, families, and pathways
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| Crossreferences | InterPro
domains - A database of protein families, domains, and functional sites
• Zinc finger, NHR/GATA-type (IPR013088)
Zinc finger, GATA-type (IPR000679)
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Sequences Consistent with the Gene Model
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| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | |||
| UniProtKB/Swiss-Prot | ||||
| UniProtKB/TrEMBL | ||||
| Maps to | ||||
| Does NOT map to | ||||
| Identified with | ||||
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Mapped Features & Mutations
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Please see
GBrowse
or insertion reports for information on insertions of transgenic
constructs and features not listed here
Type Symbol & Location Additional Notes References deletion pnr[VX1] 3R:11,865,632..11,865,645 comment=14 nucleotide deletion causing a frameshift stop truncating the protein to 514 amino acids evidence=experimental deletion pnr[VX4] 3R:11,865,646..11,865,662 comment=17 nucleotide deletion causing a frameshift stop truncating the protein to 513 amino acids evidence=experimental point mutation pnr[D4] 3R:11,864,783..11,864,783 comment=Position of mutation on reference sequence inferred by FlyBase curator based on author statement. (Figure 3 and Table 1) evidence=experimental na_change=G11864783A pr_change=E168K|pnr-PA,E116K|pnr-PB reported_na_change=G996A reported_pr_change=E?K point mutation pnr[D1] 3R:11,864,787..11,864,787 na_change=G11864787A comment=Position of mutation on reference sequence inferred by FlyBase curator based on author statement. (Figure 3 and Table 1) evidence=experimental pr_change=C169Y|pnr-PA,C117Y|pnr-PB reported_na_change=G1000A reported_pr_change=C?Y point mutation evidence=experimental comment=G to A nucleotide change at the second or third position of the Trp codon leads to a nonsense mutation (exact site of mutation unspecified) pr_change=W180|pnr-PA,W128|pnr-PB reported_na_change=G1034A reported_pr_change=W180@ point mutation pnr[D2] 3R:11,864,838..11,864,838 comment=Position of mutation on reference sequence inferred by FlyBase curator based on author statement. (Figure 3 and Table 1) evidence=experimental na_change=G11864838A pr_change=G186E|pnr-PA,G134E|pnr-PB reported_na_change=G1051A reported_pr_change=G?E point mutation pnr[D3] 3R:11,864,849..11,864,849 comment=Position of mutation on reference sequence inferred by FlyBase curator based on author statement. (Figure 3 and Table 1) evidence=experimental na_change=T11864849A pr_change=C190S|pnr-PA,C138S|pnr-PB reported_na_change=T1062A reported_pr_change=C?S uncharacterized change in nucleotide sequence pnr[Cam] 3R:11,855,858..11,856,186 evidence=experimental linked_to=BamHI-ClaI_rfrag comment=position of restriction fragment on reference sequence inferred by FlyBase curator uncharacterized change in nucleotide sequence pnr[D4R+5] 3R:11,855,858..11,859,447 linked_to=BamHI-XbaI_rfrag comment=position of restriction fragment on reference sequence inferred by FlyBase curator evidence=experimental uncharacterized change in nucleotide sequence pnr[D4R+2] 3R:11,855,858..11,859,447 evidence=experimental comment=position of restriction fragment on reference sequence inferred by FlyBase curator linked_to=BamHI-XbaI_rfrag uncharacterized change in nucleotide sequence pnr[VX6] 3R:11,863,079..11,869,089 comment=Deletion with breakpoints within this EcoRI, XhoI fragment evidence=experimental linked_to=XhoI-EcoRI_rfrag | ||||
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External Data
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| Linkouts | DEDB
- Drosophila exon database: splicing graphs
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| Crossreferences | ||||
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Expression Data
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| FlyBase-Curated Data | ||||
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Transcript and Protein data | Please see the FlyBase Gene Expression Report for details of gene expression from the literature. | |||
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Summary of Transcript Expression
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Stage Tissue/Position
Reference
embryonic stage | stage 11
dorsal ectoderm
embryonic stage | stage 11
epidermis | restricted
embryonic stage | stage 4
embryonic stage | stage 5 | late
embryonic stage | stage 6-17
epidermis | dorsal
embryonic stage | 2-12 hr
embryonic stage | stage 8 | early
proctodeum | anterior to
embryonic stage | stage 13-15
epidermis | dorsal
embryonic stage | stage 13
posterior spiracle primordium
embryonic stage | stage 11
cardiac mesoderm
larval stage | third instar stage 2
dorsal mesothoracic disc | restricted
embryonic stage | stage 8 | mid
amnioserosa
larval stage | third instar | late
eye-antennal disc | restricted
embryonic stage | stage 6-9
amnioserosa | ||||
| Marker for | ||||
| Subcellular Localization | ||||
| CV Term | ||||
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Summary of Polypeptide Expression
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Stage Tissue/Position
Reference
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| Marker for | ||||
| Subcellular Localization | ||||
| CV Term | ||||
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Microarray Data
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Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002) 
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External Data & Images
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| Linkouts | FLIGHT
- Cell culture data for RNAi and other high-throughput technologies
FlyAtlas
- Adult expression by tissue, using Affymetrix Dros2 array
GEO (NCBI)
- Gene expression data: microarray and other high-throughput technologies
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Alleles & Phenotypes
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Summary of Allele Phenotypes
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Lethality Allele Other Phenotypes Allele Sterility Allele Phenotype manifest in Allele mesothoracic tergum (with pnrMD237) mesothoracic tergum (with pnrD1) scutellar bristle (with pnrV1) | ||||
