A Database of Drosophila Genes & Genomes

 

Gene Dmel\cn

General Information
SymbolDmel\cnSpeciesD. melanogaster
NamecinnabarAnnotation symbolCG1555
Feature typeprotein_coding_geneFlyBase IDFBgn0000337
Created / Updated2003-12-02/2003-12-02
Genomic Location
Chromosome (arm)2RRecombination map2-57.5
Cytogenetic map 43E16-43E16 Sequence location2R:3,670,302..3,672,711 [-]
Map ( GBrowse ) detailed view
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Automatically generated summary

See sections below for more information
The gene cinnabar is referred to in FlyBase by the symbol cn (CG1555, FBgn0000337). It has the cytological map location 43E16. Its sequence location is 2R:3670302..3672711. Its molecular function is described as: kynurenine 3-monooxygenase activity; FAD binding. It is involved in the biological processes: ommochrome biosynthetic process; eye pigment biosynthetic process; compound eye pigmentation; tryptophan catabolic process; electron transport; tRNA processing. 223 alleles are reported. The phenotypes of these alleles are annotated with: ocellus; pigment cell; ocellus pigment granule; Malpighian tubule. It has one annotated transcript and one annotated polypeptide.

hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
43E16-43E16  
Limits computationally determined from genome sequence between P{PZ}l(2)0849208492 and P{EP}CanB2EP774  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
43E6-43E8
(determined by in situ hybridisation)  
(Howells, 1989)
Experimentally Determined Recombination Data
Location
2-57.5
(Buzzati-Traverso, 1947)
Left of (cM)
(Kornberg, 1981)
(Homyk and Pye, 1989)
Right of (cM)
(Ashburner et al., 1981)
(Ganetzky, 1977)
Notes
Molecular Map Data
Gene Order (in direction of increasing cytology)
References
Gene Order (overall orientation not stated)
References
Overall orientation not stated: CanB2- cn+
(Warren et al., 1996, Warren, 1996.4.23)
Overall orientation not stated: cn- CanB2+ Gapdh1- mus205+
(Eeken et al., 2001)
hide Gene Model & Products
Please see the GBrowse view of Dmel\cn for information on other features
detailed view FBtr0088932 FBtr0088931 FBtr0088930 FBpp0088005 FBpp0088004 FBti0071048 FBti0026054 FBti0039179 FBti0049573 FBti0066882 FBti0046607 FBti0065210 FBti0065840 FBti0045373 FBti0065982 FBti0065564 FBti0067246 FBti0018392 FBti0056477 FBti0035531 FBti0037165 FBti0066429 FBti0007694 FBti0033692
Comments on Gene Model
Known mutation in sequenced strain
EST data suggest additional 5' exon(s)
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
cn-RA
FBtr0088931
 NM_078927
  1929
  524
Additional Transcript Data & Comments
Reported size (kB)
2.2, 1.8 (northern blot)
(Warren et al., 1996)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kD)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
cn-PA  
FBpp0088005  
59.4  
524  
8.69  
  NP_523651
  AAF59196
Additional Polypeptide Data & Comments
Reported size (kD)
524 (aa)
(Warren et al., 1996)
Comments
External Data
Linkouts
PANTHER - Protein classification by function, families, and pathways
•
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
•
Pyridine nucleotide-disulphide oxidoreductase, class I (IPR001100)
Glucose-inhibited division protein A (IPR002218)
Aromatic-ring hydroxylase (IPR003042)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
AE003840
AAF59196
 
AF317317
 
AF317318
 
AF317319
AAK07882
 
AY071296
AAL48918
 
AZ933382
 
BI236592
 
BI239014
 
CZ467909
 
CZ469073
 
CZ469911
 
CZ469953
 
CZ470141
 
CZ478570
 
CZ480819
 
CZ482641
 
U56245
AAC47351
 
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
    Maps to
    Does NOT map to
    Identified with
    (BDGP Project Members, 2000-)
    hide Mapped Features & Mutations
    Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here
    Type
    Symbol & Location
    Additional Notes
    References
    hide External Data
    Linkouts
    Crossreferences
    hide Expression Data
    FlyBase-Curated Data
    Transcript and
    Protein data     		Please see the FlyBase Gene Expression Report for details of gene expression from the literature.
    hide Summary of Transcript Expression
    Stage
    Tissue/Position
    Reference
     larval stage-pupal stage
     
    (Warren et al., 1996)
    Marker for
      Subcellular Localization
      CV Term
      hide Summary of Polypeptide Expression
      Stage
      Tissue/Position
      Reference
      Marker for
        Subcellular Localization
        CV Term
        hide External Data & Images
        Linkouts
        FLIGHT - Cell culture data for RNAi and other high-throughput technologies
        •
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        •
        GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies
        •
        BDGP expression data
        •
        Show all BDGP original images, annotations and embryonic microarray data for cn
        FlyExpress - Embryonic expression images (BDGP data)
        •
        Show all FlyExpress processed images for cn
        hide Alleles & Phenotypes
        hide Summary of Allele Phenotypes
        Other Phenotypes
        Allele
        visible
        visible | recessive
        eye color defective
        eye color defective | recessive
        Sterility
        Allele
        female sterile
        female sterile | recessive
        male sterile
        Phenotype manifest in
        Allele
        ocellus
        pigment cell
        ocellus pigment granule
        Malpighian tubule
        hide Classical Alleles ( 221 )
        For All Classical Alleles Show

        Allele of cnClassMutagenStocksKnown lesion
        cn+c
          		0 --
          cn+e
            		0 --
            cn10P0 --
            cn11P0 --
            cn12Phypomorph0 --
            cn13P0 --
            cn14P0 --
            cn15P0 --
            cn16P0 --
            cn17P0 --
            cn18P0 --
            cn19P0 --
            cn11587 Yes
            cn20P0 --
            cn21P0 --
            cn22P0 --
            cn23P0 --
            cn24P0 --
            cn25P0 --
            cn26P0 --
            cn27P0 --
            cn28P0 --
            cn29P0 --
            cn2hypomorph284 Yes
            cn2Pamorph6 --
            cn30P0 --
            cn31Pamorph0 --
            cn35khypomorph3 Yes
            cn36c
              		0 --
              cn38jhypomorph
                		0 --
                cn3amorph
                  		2 Yes
                  cn45j0 --
                  cn4amorph
                    		3 Yes
                    cn4P0 --
                    cn57e0 --
                    cn5P0 --
                    cn67d0 --
                    cn6P0 --
                    cn72a20 --
                    cn74b10 --
                    cn74b20 --
                    cn74b30 --
                    cn74b40 --
                    cn74c20 --
                    cn74c50 --
                    cn74c70 --
                    cn74c80 --
                    cn74c90 --
                    cn74d10 --
                    cn74d40 --
                    cn74d50 --
                    cn74d70 --
                    cn74d80 --
                    cn75a20 --
                    cn76b0 --
                    cn76e20 --
                    cn76i0 --
                    cn76k10 --
                    cn76k20 --
                    cn77a100 --
                    cn77a20 --
                    cn77a30 --
                    cn77a40 --
                    cn77a90 --
                    cn77c20 --
                    cn78amorph0 --
                    cn78a0 --
                    cn78b10 --
                    cn78f0 --
                    cn78g0 --
                    cn78j20 --
                    cn78k10 --
                    cn78l0 --
                    cn79b100 --
                    cn79b110 --
                    cn79b150 --
                    cn79b50 --
                    cn79b70 --
                    cn79b80 --
                    cn79c0 --
                    cn79d120 --
                    cn79d150 --
                    cn79d18