Gene Dmel\CG4691

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General Information

Symbol

Dmel\CG4691

Species

D. melanogaster

Name

CG4691

Annotation symbol

CG4691

Feature type

protein_coding_gene

FlyBase ID

FBgn0028870

Created / Updated

2003-12-01/2003-12-01

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

35B5-35B5

Sequence location

2L:14,760,767..14,761,933 [+]

Map ( GBrowse )

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol CG4691 (FBgn0028870). It has the cytological map location 35B5. Its sequence location is 2L:14760767..14761933. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

35B5-35B5

Limits computationally determined from genome sequence between P{EP}elB^EP2039&P{PZ}osp^rJ571 and P{lacW}Su(H)^k07904

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Molecular Map Data

Gene Order (in direction of increasing cytology)

References

In direction of increasing cytology: CG15281+ CG4691+ CSN1a+

(Ashburner et al., 1999)

Gene Order (overall orientation not stated)

References

Gene Model & Products

Please see the GBrowse view of Dmel\CG4691 for information on other features

Comments on Gene Model

EST data support existence of multiple transcripts

Multiple ESTs homologous to non-coding strand of this gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG4691-RA

FBtr0080670

NM_135875

1167

262

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kD)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG4691-PA

FBpp0080232

30.8

262

10.38

NP_609719

AAF53408

Additional Polypeptide Data & Comments

Reported size (kD)

Comments

External Data

Linkouts

PANTHER - Protein classification by function, families, and pathways

•

FBgn0028870

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Protein of unknown function DUF1431, cysteine-rich, Drosophila (IPR006611)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9V3K5

Maps to

DS06874

(Ashburner et al., 1999.10.12)

Does NOT map to

Identified with

GH20441

(BDGP Project Members, 2000-, Oliver, 2001.8.16)

Mapped Features & Mutations

Please see GBrowse or insertion reports for information on insertions of transgenic constructs and features not listed here

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

DEDB - Drosophila exon database: splicing graphs

•

7690

Crossreferences

Expression Data

FlyBase-Curated Data

Transcript and
Protein data

Please see the FlyBase Gene Expression Report for details of gene expression from the literature.

Summary of Transcript Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Summary of Polypeptide Expression

Stage

Tissue/Position

Reference

Marker for

Subcellular Localization

CV Term

Microarray Data

Developmental timecourse, Costello et al., 2008 (Original data from Arbeitman et al., 2002)

Untitled Document detailed view

AI389302

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0028870

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0028870

Alleles & Phenotypes

Summary of Allele Phenotypes

Phenotype manifest in

Allele

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG4691	Class	Mutagen	Stocks	Known lesion
CG4691^MB00873			1	--

Alleles Carried on Transgenic Constructs ( 1 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG4691	Class	Mutagen	Stocks	Known lesion
CG4691^GD11395		in vitro construct \| RNAi in vitro construct \| regulatory fusion	1	Yes

Aneuploid Aberrations

Useful deficiency

Df(2L)A220

Useful duplication

Dp(2;2)GYL

Disrupted in

Df(2L)Exel8033

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD11395}

Insertions

Type of insertions

Name

Expression data

insertion of enhancer trap binary system

Mi{ET1}CG4691^MB00873

Related Comments

Please look at the allele reports for the complete phenotype data

Gene Ontology: Function, Process & Cellular Component ( 0 )

Molecular Function

CV term

Evidence

References

Biological Process

CV term

Evidence

References

Cellular Component

CV term

Evidence

References

Sequence Ontology: Class of Gene

protein_coding_gene

nuclear_gene

Interactions & Pathways

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG4691 allele

Gene

References

External Data

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

60879

Orthologs

Genome-wide drosophilid orthologs

Dana\GF14894

Dere\GG25129

Dsec\GM15754

Dsim\GD23976

Dyak\GE19047

Curated drosophilid orthologs

Dyak\GE19047

Linkouts

Functional Complementation between Species

Inter-Species Misexpression Data

Produces phenotype in

Produces NO phenotype in

Stocks & Reagents

Stocks Listed in FlyBase ( 2 )

VDRC

v21920

w¹¹¹⁸ P{GD11395}v21920

Bloomington

22919

y¹ w^67c23; Mi{ET1}CG4691^MB00873

Genomic Clones ( 1 )

BACR39O07

cDNA Clones ( 61 )

cDNA Clones, Fully Sequenced

BDGP DGC clones

GH20441

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Affy Oligo

Linkouts

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0028870

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0028870

Antibody Information

Other Information

Discoverer

Etymology

Identification

Position Effect Variegation Data

Relationship to Other Genes

Source for database identity of

Source for identity of: BG:DS06874.1 CG4691

(Kodira, 1999.11)

Source for database merge of

Source for merge of: CG4691 anon-WO0140519.47 Source for merge of CG4691 anon-WO0140519.47 was sequence comparison (date:051113).

(FlyBase, 1996-)

Additional comments

Comments About Role

Comments About Molecular Function

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_135875

RefSeq (Proteins)

•

NP_609719

DDBJ / EMBL / GenBank

UniProtKB/TrEMBL

•

Q9V3K5

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Protein of unknown function DUF1431, cysteine-rich, Drosophila (IPR006611)

Linkouts

BioGRID - Interaction data, including yeast 2-hybrid and genetic interactions

•

60879

DEDB - Drosophila exon database: splicing graphs

•

7690

DRSC - RNAi screening (Harvard): high-throughput cell culture data and design

•

FBgn0028870

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0028870

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0028870

GEO (NCBI) - Gene expression data: microarray and other high-throughput technologies

•

FBgn0028870

GenomeRNAi - RNAi phenotypes (Heidelberg): high-throughput cell culture data

•

FBgn0028870

PANTHER - Protein classification by function, families, and pathways

•

FBgn0028870

Synonyms & Secondary IDs ( 3 )

Reported As

Symbol Synonym

anon-WO0140519.47

BG:DS06874.1

(Ashburner et al., 1999.10.12, Ashburner et al., 1999, Ashburner et al., 1999, Giot et al., 2003, )

CG4691

Name Synonym

CG4691

Secondary FlyBase IDs

FBgn0044583

References ( 12 )

Research paper

Ashburner et al., 1999, Genetics 153(1): 179--219: An exploration of the sequence of a 2.9-Mb region of the genome of Drosophila melanogaster. The Adh region. [FBrf0111326]

Supplementary material

Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]
Ashburner et al., 1999, Genetics 153(1):: Table S2. Genes, known and predicted, that have been determined on the sequence of the Adh region. All genes are protein coding, unless indicated tscan in the prediction column, these are tRNAs. [FBrf0112151]

Personal communication to FlyBase

Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Bellen, 2006.10.16, MBinsertSet693.xml: MBinsertSet693.xml [FBrf0191807]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348).: File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492]
Ashburner et al., 1999.10.12, Adh.: Adh. [FBrf0112153]

FlyBase analysis

FlyBase, 1996-, FlyBase inference based on genome sequence analysis.: FlyBase inference based on genome sequence analysis. [FBrf0104946]

Curated genome annotation

Kodira, 1999.11, [Annotations performed at the Celera Jamboreee.]: [Annotations performed at the Celera Jamboreee.] [FBrf0126678]

Computer file

BDGP Project Members, 2000-, Berkeley Drosophila Genome Project.: Berkeley Drosophila Genome Project. [FBrf0125078]

Patent

Greenspan, 2001.6.7, World Patent 0140519-A:: Methods for identifying modulators for balance related disorders. [FBrf0141245]