Allele Dmel\let-7^MtnA.PR

General Information
Symbol	Dmel\let-7^MtnA.PR	Species	D. melanogaster
Name	Metallothionein A promoter construct of Ruby	FlyBase ID	FBal0213136
Feature type	allele	Created / Updated	2008-02-21/2008-02-21
Associated gene	Dmel\let-7

Allele class
Mutagen	in vitro construct \| regulatory fusion
Nature of the Allele
Allele class
Mutagen	in vitro construct \| regulatory fusion (Ruby et al., 2007, Ruby et al., 2007)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Contains a 780bp fragment centred on the let-7 hairpin. (Ruby et al., 2007) A MtnA promoter drives expression of let-7 sequences. (Ruby et al., 2007)
Assay mode	Drosophila cell culture (Ruby et al., 2007, Ruby et al., 2007)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Comments
	Carried in a plasmid and transfected into S2 cells. (Ruby et al., 2007) Carried in plasmid "pCJ24" and transfected into S2 cells. (Ruby et al., 2007)
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	let-7^MtnA.PR
Name Synonym	Metallothionein A promoter construct of Ruby
Secondary FlyBase IDs

References ( 2 )
Research paper	Ruby et al., 2007, Nature 448(7149): 83--86 Intronic microRNA precursors that bypass Drosha processing. [FBrf0201222]
Supplementary material	Ruby et al., 2007, Nature 448(7149): Supplementary information. [FBrf0202573]

Allele Dmel\let-7MtnA.PR

Allele Dmel\let-7^MtnA.PR