A Database of Drosophila Genes & Genomes

 

Allele Dmel\mir-7Scer\UAS.cLa

General Information
SymbolDmel\mir-7Scer\UAS.cLaSpeciesD. melanogaster
NameSaccharomyces cerevisiae UAS construct a of LaiFlyBase IDFBal0190939
Feature typealleleCreated / Updated2006-08-22/2006-08-22
Associated geneDmel\mir-7
Allele class
Mutagenin vitro construct | regulatory fusion
hide Nature of the Allele
Allele class
Mutagen
in vitro construct | regulatory fusion
(Lai et al., 2005, Aboobaker et al., 2005)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Construct: Scer\UAS regulatory sequences drive expression of mir-7.
      (Lai et al., 2005)
      Construct: Scer\UAS regulatory sequences drive expression of mir-7 sequences.
      (Aboobaker et al., 2005)
      Assay mode
      In transgenic Drosophila (intraspecific)
      (Lai et al., 2005, Aboobaker et al., 2005)
      Carried in construct
      P{UAS-mir-7.L}
      (Lai et al., 2005, Aboobaker et al., 2005)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      visible, with Scer\GAL4dpp.blk1
      (Lai et al., 2005)
      hide Phenotype Manifest In
      wing, with Scer\GAL4dpp.blk1
      (Lai et al., 2005)
      1st posterior cell, with Scer\GAL4dpp.blk1
      (Lai et al., 2005)
      wing, with Scer\GAL4ptc-559.1
      (Aboobaker et al., 2005)
      hide Detailed Description
      Statement
      Reference
      Expression of mir-7Scer\UAS.cLa under the control of Scer\GAL4dpp.blk1 results in a notched wing and a reduced L3-L4 intervein region. More generalised expression of mir-7Scer\UAS.cLa through Scer\GAL4Bx-MS1096 induces strong thickening of wing veins.
      (Lai et al., 2005)
      mir-7Scer\UAS.cLa mutants (under the activation of Scer\GAL4ptc-559.1)exhibit wing notching and bristle tufting.
      (Aboobaker et al., 2005)
      hide Interactions
      hide Phenotypic Class
      hide Phenotype Manifest In
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Comments
      hide Stocks ( 0 )
      hide Notes on Origin
      Discoverer
      hide Synonyms & Secondary IDs ( 2 )
      Reported As
      Symbol Synonym
      mir-7Scer\UAS.cLa
       
      Name Synonym
      Saccharomyces cerevisiae UAS construct a of Lai
      (Lai et al., 2005)
      Secondary FlyBase IDs
        hide References ( 2 )
        Research paper
        Aboobaker et al., 2005, Proc. Natl. Acad. Sci. USA 102(50): 18017--18022
        Drosophila microRNAs exhibit diverse spatial expression patterns during embryonic development. [FBrf0191424]
        Lai et al., 2005, Genes Dev. 19(9): 1067--1080
        Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs. [FBrf0187594]