Allele Dmel\Lim1^7B2

General Information
Symbol	Dmel\Lim1^7B2	Species	D. melanogaster
Name		FlyBase ID	FBal0119469
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\Lim1

Allele class
Mutagen	P-element activity
Nature of the Allele
Allele class
Mutagen	P-element activity (Tsuji et al., 2000)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype	Lim1^P0092 (Tsuji et al., 2000)
Nature of the lesion	Statement Reference Imprecise excision of the P{lArB} element, resulting in deletion of the predicted RNA start site, the first exon and a portion of the first intron. (Tsuji et al., 2000)
Assay mode
Cytology
Phenotypic Data
Phenotypic Class
	visible \| recessive (Tsuji et al., 2000)
Phenotype Manifest In
	unguis (Tsuji et al., 2000) antenna (Tsuji et al., 2000) arista (Tsuji et al., 2000) femur (Tsuji et al., 2000) coxa (Tsuji et al., 2000) tibia (Tsuji et al., 2000)
Detailed Description
	Statement Reference The pulvilli and empodia are usually present in legs of homozygous flies, but claws are frequently lost. The antenna is absent in about half of all cases. When the antenna is present, the arista is deformed and reduced in size. The femur is extensively reduced in size and the coxa is generally missing or present only as a small bulb-like structure. The tibia is bent and fused with the femur, although essentially normal characteristic structures of the tibia, such as transverse rows of bristles, preapical bristles, tibial sense organs and tibial sensilla trichodea are present. (Tsuji et al., 2000)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement Reference Lim1^7B2 has visible phenotype, enhanceable by al¹ (Tsuji et al., 2000)
Phenotype Manifest In
Other
Statement Reference Lim1^7B2, al¹ has empodium phenotype (Tsuji et al., 2000, Tsuji et al., 2000) Lim1^7B2, al¹ has pulvillus phenotype (Tsuji et al., 2000, Tsuji et al., 2000)
Additional Comments
Genetic Interactions
Statement Reference In Lim1^7B2 ; al¹ double mutant flies, not only claws but also empodia and pulvilli are frequently lost. (Tsuji et al., 2000)
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	Lim1^7B2
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Kojima et al., 2005, Dev. Biol. 279(2): 434--445 A concerted action of a paired-type homeobox gene, aristaless, and a homolog of Hox11/tlx homeobox gene, clawless, is essential for the distal tip development of the Drosophila leg. [FBrf0183860] Tsuji et al., 2000, Development 127(20): 4315--4323 Requirements of Lim1, a Drosophila LIM-homeobox gene, for normal leg and antennal development. [FBrf0130121]

Allele Dmel\Lim17B2

Allele Dmel\Lim1^7B2