A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Dmel\iab-445

General Information
SymbolDmel\iab-445SpeciesD. melanogaster
NameFlyBase IDFBal0102677
Feature typealleleCreated / Updated2006-08-22/2006-08-22
Associated geneDmel\iab-4
Allele class
MutagenX ray
hide Nature of the Allele
Allele class
Mutagen
X ray
(Karch et al., 1985)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Lesion mapped to: 78.5-82 kb.
      (Karch et al., 1985)
      Break lies in the iab-4 transcription unit.
      (Cumberledge et al., 1990)
      Assay mode
      Caused by aberration
      T(2;3)iab445
      (Cumberledge et al., 1990, Karch et al., 1985, )
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      viable
      (Jijakli and Ghysen, 1992)
      visible | homeotic
      (Karch et al., 1985)
      hide Phenotype Manifest In
      ovary
      (Cumberledge et al., 1992)
      oviduct
      (Cumberledge et al., 1992)
      testis
      (Cumberledge et al., 1992)
      gonad | precursor
      (Warrior, 1994)
      adult abdominal segment 2
      (Karch et al., 1985)
      hide Detailed Description
      Statement
      Reference
      Partial transformation of the second adult abdominal segment to the fourth or third.
      (Karch et al., 1985)
      Sometimes form ovaries. The ovary-oviduct junctions are abnormal and egg transfer from the ovary to the uterus is blocked in the adults. Often only one mature testis with sperm is found in the males.
      (Cumberledge et al., 1992)
      Defective in gonad assembly.
      (Warrior, 1994)
      hide Interactions
      hide Phenotypic Class
      hide Phenotype Manifest In
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Comments
      hide Stocks ( 0 )
      hide Notes on Origin
      Discoverer
      R. Baker.
      Induced with: abd-Aiab4-45.
      (Cumberledge et al., 1990)
      hide Comments
      Mutations in iab-4 have effects on the abd-A transcription unit, so such mutations are considered to be simultaneously mutant for iab-4 and abd-A.
       
      hide Synonyms & Secondary IDs ( 4 )
      Reported As
      Symbol Synonym
      iab445
       
      iab-445
       
      iab411045
       
      iab431616.1045
       
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 5 )
        Research paper
        Warrior, 1994, Dev. Biol. 166(1): 180--194
        Primordial germ cell migration and the assembly of the Drosophila embryonic gonad. [FBrf0076121]
        Cumberledge et al., 1992, Development 115(2): 395--402
        Gonad formation and development requires the abd-A domain of the Bithorax complex in Drosophila melanogaster. [FBrf0055868]
        Jijakli and Ghysen, 1992, Int. J. Dev. Biol. 36(1): 93--99
        Segmental determination in Drosophila central nervous system: analysis of the abdominal-A region of the Bithorax complex. [FBrf0056377]
        Cumberledge et al., 1990, Proc. Natl. Acad. Sci. USA 87: 3259--3263
        Characterization of two RNAs transcribed from the cis-regulatory region of the abd-A domain within the Drosophila bithorax complex. [FBrf0052838]
        Karch et al., 1985, Cell 43: 81--96
        The abdominal region of the Bithorax complex. [FBrf0042053]