Allele Rnor\SAP97^Scer\UAS.cTa

General Information
Symbol	Rnor\SAP97^Scer\UAS.cTa	Species	R. norvegicus
Name	Saccharomyces cerevisiae UAS construct a of Thomas	FlyBase ID	FBal0060585
Feature type	allele	Created / Updated	2006-08-20/2006-08-20
Associated gene	Rnor\SAP97

Allele class
Mutagen	in vitro construct \| regulatory fusion
Nature of the Allele
Allele class
Mutagen	in vitro construct \| regulatory fusion (Thomas et al., 1997)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: A Rnor\SAP97 cDNA (31f2), comprising 225bp 5' untranslated sequences, a complete open reading frame (2697bp) and approximately 1.3kb 3' untranslated sequences, is expressed under the control of Scer\UAS regulatory sequences. (Thomas et al., 1997)
Assay mode	In transgenic Drosophila (allele of foreign species in genome of drosophilid) (Thomas et al., 1997)
Carried in construct	P{UAS-Rat\SAP97.T} (Thomas et al., 1997, Thomas et al., 1997)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressor of
Statement Reference Scer\GAL4^da.G32/Rnor\SAP97^Scer\UAS.cTa is a suppressor \| partially of tumorigenic phenotype of dlg1⁷ (Thomas et al., 1997) Scer\GAL4^elav.PLu/Rnor\SAP97^Scer\UAS.cTa is a suppressor \| partially of tumorigenic phenotype of dlg1⁷ (Thomas et al., 1997)
Phenotype Manifest In
Suppressor of
Statement Reference Scer\GAL4^da.G32/Rnor\SAP97^Scer\UAS.cTa is a suppressor \| partially of imaginal disc phenotype of dlg1⁷ (Thomas et al., 1997) Scer\GAL4^da.G32/Rnor\SAP97^Scer\UAS.cTa is a suppressor \| partially of phenotype of dlg1² (Thomas et al., 1997) Scer\GAL4^da.G32/Rnor\SAP97^Scer\UAS.cTa is a suppressor \| partially of phenotype of dlg1⁵ (Thomas et al., 1997)
NOT Suppressor of
Statement Reference Scer\GAL4^da.G32/Rnor\SAP97^Scer\UAS.cTa is a non-suppressor of bouton phenotype of dlg1⁷ (Thomas et al., 1997)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference Partially rescues the imaginal disc and brain tumour phenotypes of hemizygous dlg1⁷ males when expressed using Scer\GAL4^da.G32, resulting in viable adults in some cases when the flies contain two copies of Rnor\SAP97^Scer\UAS.cTa. Hemizygous dlg1² or dlg1⁵ males are partially rescued by one copy of Rnor\SAP97^Scer\UAS.cTa expressed using Scer\GAL4^da.G32. The neuromuscular junction presynaptic phenotype but not the tumour phenotype of hemizygous dlg1⁷ males is rescued when Rnor\SAP97^Scer\UAS.cTa is expressed using Scer\GAL4^elav.PLu. (Thomas et al., 1997) Rescues the increased number of active zones seen in hemizygous dlg1⁷ type I boutons if targeted to both pre- and postsynaptic cells using Scer\GAL4^unspecified. (Thomas et al., 1997)
Complementation & Rescue Data
Comments
Stocks ( 0 )

Notes on Origin
Discoverer

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Rat\SAP97^UAS.cTa Rnor\SAP97^Scer\UAS.cTa
Name Synonym	Saccharomyces cerevisiae UAS construct a of Thomas (Thomas et al., 1997)
Secondary FlyBase IDs

References ( 2 )
Research paper	Thomas et al., 1997, Mech. Dev. 62(2): 161--174 Functional expression of rat synapse-associated proteins SAP97 and SAP102 in Drosophila dlg-1 mutants: effects on tumor suppression and synaptic bouton structure. [FBrf0093753] Thomas et al., 1997, Neuron 19(4): 787--799 Synaptic clustering of the cell adhesion molecule fasciclin II by discs-large and its role in the regulation of presynaptic structure. [FBrf0099054]

Allele Rnor\SAP97Scer\UAS.cTa

Allele Rnor\SAP97^Scer\UAS.cTa