A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Scer\GAL4sim.PS

General Information
SymbolScer\GAL4sim.PSSpeciesS. cerevisiae
Namesingle-minded promoter construct of ScholzFlyBase IDFBal0058755
Feature typealleleCreated / Updated2006-05-31/2006-05-31
Associated geneScer\GAL4
Allele class
Mutagenin vitro construct | regulatory fusion
hide Nature of the Allele
Allele class
Mutagen
in vitro construct | regulatory fusion
(Golembo et al., 1996, Scholz et al., 1997, Scholz et al., 1997)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Construct: sim promoter fragment drives expression of Scer\GAL4.
      (Golembo et al., 1996)
      3.5kb EcoRV sim promoter fragment drives expression of Scer\GAL4.
      (Scholz et al., 1997, Scholz et al., 1997)
      Assay mode
      In transgenic Drosophila (allele of foreign species in genome of drosophilid)
      (Scholz et al., 1997, Scholz et al., 1997, Golembo et al., 1996)
      Carried in construct
      P{GAL4-sim.S}
      (Wood et al., 2006, Franch-Marro et al., 2005, Shandala et al., 2003, Bergmann et al., 2002, Yoshikawa et al., 2003, Menne et al., 1997, Giesen et al., 2003, Merianda et al., 2005, Dorfman et al., 2002, Fradkin et al., 2004, Gallio et al., 2004, McGovern et al., 2003, Steigemann et al., 2004, Desbordes and Sanson, 2003, Hummel et al., 2000, Hummel et al., 2000, Olofsson and Page, 2005, Onel et al., 2004, Miguel-Aliaga and Thor, 2004, Wojtowicz et al., 2004, Schimmelpfeng et al., 2001, Sanchez Soriano and Russell, 1998, Page, 2003, Vorbruggen and Jackle, 1997, Scholz et al., 1997, Luer et al., 1997, Becker et al., 1997, Scholz et al., 1997, Golembo et al., 1996, Bossing and Brand, 2006, Boyle et al., 2006, Hulsmeier et al., 2007, Schimmelpfeng et al., 2006)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      cell death increase, with hhScer\UAS.cIa
      (Bossing and Brand, 2006)
      neuroanatomy defective, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      neuroanatomy defective, with EphrinScer\UAS.cBa
      (Bossing and Brand, 2002)
      neuroanatomy defective, with EphrinScer\UAS.T:Hsap\MYC
      (Boyle et al., 2006)
      hide Phenotype Manifest In
      trachea, with bnlScer\UAS.cSa
      (Dorfman et al., 2002)
      embryonic central brain, with rhoScer\UAS.cdCa
      (Page, 2003)
      ganglionic branch 1 & embryo, with rhoScer\UAS.cBa
      (Gallio et al., 2004)
      midline glial cell, with pntP1.Scer\UAS
      (Scholz et al., 1997, Scholz et al., 1997)
      ventral nerve cord & embryo, with PvrDN.Scer\UAS
      (Olofsson and Page, 2005)
      commissure, with JraAsp.Scer\UAS
      (Scholz et al., 1997, Scholz et al., 1997)
      ventral nerve cord commissure, with Cnx99AEP3522
      (McGovern et al., 2003)
      ventral nerve cord, with Cnx99AEP3522
      (McGovern et al., 2003)
      medial longitudinal fascicle, with Cnx99AEP3522
      (McGovern et al., 2003)
      anterior commissure, with Wnt5EY03178
      (Yoshikawa et al., 2003)
      embryonic central nervous system, with kuzDN.Scer\UAS
      (Schimmelpfeng et al., 2001)
      longitudinal connective, with kuzDN.Scer\UAS
      (Schimmelpfeng et al., 2001)
      embryonic somatic muscle, with kuzDN.Scer\UAS
      (Schimmelpfeng et al., 2001)
      ventral nerve cord commissure, with shiK44A.Scer\UAS
      (Onel et al., 2004)
      commissure, with EgfrDN.Scer\UAS
      (Scholz et al., 1997, Scholz et al., 1997)
      anterior commissure, with Wnt5Scer\UAS.cFa
      (Fradkin et al., 2004)
      posterior commissure, with DscamScer\UAS.cWa, Scer\GAL4eg-Mz360
      (Wojtowicz et al., 2004)
      commissure, with EphrinScer\UAS.cBa
      (Bossing and Brand, 2002)
      embryonic neuron, with EphrinScer\UAS.cBa
      (Bossing and Brand, 2002)
      commissure, with aopACT.Scer\UAS
      (Scholz et al., 1997, Scholz et al., 1997)
      longitudinal connective, with aopACT.Scer\UAS
      (Scholz et al., 1997, Scholz et al., 1997)
      embryonic somatic muscle | lateral, with Df(3R)DG4, srScer\UAS.cBa
      (Becker et al., 1997)
      VUM neuron, with Rac1V12.Scer\UAS
      (Hummel et al., 2000)
      ventral nerve cord commissure, with Rac1V12.Scer\UAS
      (Hummel et al., 2000)
      aCC neuron, with spis.Scer\UAS
      (Menne et al., 1997)
      pCC neuron, with spis.Scer\UAS
      (Menne et al., 1997)
      dorsal neurohemal organ, with spis.Scer\UAS
      (Luer et al., 1997)
      ventral nerve cord commissure, with CG11966GS-A304
      (McGovern et al., 2003)
      embryonic/first instar larval cuticle, with wgScer\UAS.cLa
      (Desbordes and Sanson, 2003)
      denticle, with wgScer\UAS.cLa
      (Desbordes and Sanson, 2003)
      axon, with futschEP1419
      (Hummel et al., 2000)
      embryonic/larval somatic muscle | ventral, with srb.Scer\UAS
      (Vorbruggen and Jackle, 1997)
      midline glial cell | ectopic, with BacA\p35Scer\UAS.cHa
      (Giesen et al., 2003)
      VUM neuron, with HemScer\UAS.cHa
      (Hummel et al., 2000)
      ventral midline, with hhScer\UAS.cIa
      (Bossing and Brand, 2006)
      anterior commissure, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      ventral midline glia, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      midline neuronal primordium, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      posterior commissure, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      MP1 neuron, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      UMI interneuron & axon, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      VUM neuron & axon, with enScer\UAS.cYa
      (Bossing and Brand, 2006)
      embryonic central nervous system, with EphrinScer\UAS.T:Hsap\MYC
      (Boyle et al., 2006)
      commissure, with EphrinScer\UAS.T:Hsap\MYC
      (Boyle et al., 2006)
      commissure, with EphrinΔIC.Scer\UAS.T:Hsap\MYC
      (Boyle et al., 2006)
      embryonic hemocyte, with Pvf2d02444
      (Wood et al., 2006)
      hide Detailed Description
      Statement
      Reference
      hide Interactions
      hide Phenotypic Class
      hideNOT Suppressor of
      Statement
      Reference
      sliScer\UAS.cKa/Scer\GAL4sim.PS is a non-suppressor of neuroanatomy defective phenotype of ptcunspecified
      (Merianda et al., 2005)
      sliScer\UAS.cKa, Scer\GAL4sim.PS, Scer\GAL4Scer\UAS.cHa is a non-suppressor of neuroanatomy defective phenotype of ptcunspecified
      (Merianda et al., 2005)
      hide Phenotype Manifest In
      hideEnhanced by
      Statement
      Reference
      Scer\GAL4sim.PS, bnlScer\UAS.cSa has trachea phenotype, enhanceable by srScer\UAS.cBa
      (Dorfman et al., 2002)
      hideSuppressed by
      Statement
      Reference
      Scer\GAL4sim.PS, Wnt5Scer\UAS.cFa has anterior commissure phenotype, suppressible by porPB16
      (Fradkin et al., 2004)
      EphrinScer\UAS.cBa, Scer\GAL4sim.PS has commissure phenotype, suppressible by EphdsRNA.cBa
      (Bossing and Brand, 2002)
      Scer\GAL4sim.PS, Wnt5EY03178 has anterior commissure phenotype, suppressible by drlRed2
      (Yoshikawa et al., 2003)
      EphrinScer\UAS.T:Hsap\MYC, Scer\GAL4sim.PS has commissure phenotype, suppressible by Ephx652
      (Boyle et al., 2006)
      hideNOT suppressed by
      Statement
      Reference
      Scer\GAL4sim.PS, wgScer\UAS.cLa has denticle phenotype, non-suppressible by dlp3'.dsRNA/Scer\GAL4sim.PS/dally3'.dsRNA
      (Desbordes and Sanson, 2003, Desbordes and Sanson, 2003)
      Scer\GAL4sim.PS, wgScer\UAS.cLa has denticle phenotype, non-suppressible by dlp3'.dsRNA/Scer\GAL4sim.PS
      (Desbordes and Sanson, 2003, Desbordes and Sanson, 2003)
      hideEnhancer of
      Statement
      Reference
      Scer\GAL4sim.PS/BacA\p35Scer\UAS.cHa is an enhancer of midline glial cell | ectopic phenotype of dibunspecified
      (Giesen et al., 2003)
      hideSuppressor of
      Statement
      Reference
      Rac1V12.Scer\UAS/Scer\GAL4sim.PS is a suppressor | partially of ventral nerve cord commissure phenotype of HemJ4-48
      (Hummel et al., 2000)
      Rac1V12.Scer\UAS/Scer\GAL4sim.PS is a suppressor | partially of longitudinal connective phenotype of HemJ4-48
      (Hummel et al., 2000)
      Mmus\Sox2Scer\UAS.cSa/Scer\GAL4sim.PS is a suppressor of ventral nerve cord commissure phenotype of Dr72/Df(3L)fz-GS1a
      (Sanchez Soriano and Russell, 1998)
      Mmus\Sox2Scer\UAS.cSa/Scer\GAL4sim.PS is a suppressor of longitudinal connective phenotype of Dr72/Df(3L)fz-GS1a
      (Sanchez Soriano and Russell, 1998)
      rhoScer\UAS.cBa/Scer\GAL4sim.PS is a suppressor | partially of embryonic/larval ganglionic branch phenotype of ruunspecified
      (Gallio et al., 2004)
      Scer\GAL4sim.PS/NetBScer\UAS.cHa is a suppressor | partially of ventral nerve cord commissure & embryo phenotype of sizU112
      (Onel et al., 2004)
      hideNOT Suppressor of
      Statement
      Reference
      dlp3'.dsRNA, Scer\GAL4sim.PS, dally3'.dsRNA is a non-suppressor of denticle phenotype of Scer\GAL4sim.PS, wgScer\UAS.cLa
      (Desbordes and Sanson, 2003, Desbordes and Sanson, 2003)
      dlp3'.dsRNA/Scer\GAL4sim.PS is a non-suppressor of denticle phenotype of Scer\GAL4sim.PS, wgScer\UAS.cLa
      (Desbordes and Sanson, 2003, Desbordes and Sanson, 2003)
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Rescues
      sizP2.Scer\UAS/Scer\GAL4sim.PS rescues sizU112
      (Onel et al., 2004)
      sizP1.Scer\UAS/Scer\GAL4sim.PS rescues sizU112
      (Onel et al., 2004)
      Partially rescues
      simScer\UAS.cMa/Scer\GAL4sim.PS partially rescues sim2
      (Menne et al., 1997)
      Scer\GAL4sim.PS/kayScer\UAS.cEa partially rescues kayunspecified
      (Giesen et al., 2003)
      Scer\GAL4sim.PS/DScer\UAS.cSa partially rescues Dr72/Df(3L)fz-GS1a
      (Sanchez Soriano and Russell, 1998)
      DΔC75.Scer\UAS/Scer\GAL4sim.PS partially rescues Dr72/Df(3L)fz-GS1a
      (Sanchez Soriano and Russell, 1998)
      HemScer\UAS.cHa/Scer\GAL4sim.PS partially rescues HemJ4-48
      (Hummel et al., 2000)
      Fails to rescue
      Wnt5Scer\UAS.cFa/Scer\GAL4sim.PS fails to rescue Wnt5400
      (Fradkin et al., 2004)
      SdcScer\UAS.cSa/Scer\GAL4sim.PS fails to rescue Sdcunspecified
      (Steigemann et al., 2004)
      Scer\GAL4sim.PS/β-SpecScer\UAS.cHa fails to rescue β-Specunspecified/β-Specunspecified
      (Hulsmeier et al., 2007)
      Comments
      hide Stocks ( 0 )
      hide Notes on Origin
      Discoverer
      hide Synonyms & Secondary IDs ( 3 )
      Reported As
      Symbol Synonym
      GAL4sim.PS
       
      Scer\GAL4sim.PS
       
      Name Synonym
      single-minded promoter construct of Scholz
      (Golembo et al., 1996)
      Secondary FlyBase IDs
        hide References ( 34 )
        Generate a list of
        List References by type
        hide Recent research papers ( 5 )
        Hulsmeier et al., 2007, Development 134(4): 713--722
        Distinct functions of α-Spectrin and β-Spectrin during axonal pathfinding. [FBrf0194635]
        Bossing and Brand, 2006, Development 133(6): 1001--1012
        Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline. [FBrf0190277]
        Boyle et al., 2006, Development 133(9): 1845--1854
        Drosophila Eph receptor guides specific axon branches of mushroom body neurons. [FBrf0190278]
        Schimmelpfeng et al., 2006, Mech. Dev. 123(6): 487--499
        Mummy encodes an UDP-N-acetylglucosamine-dipohosphorylase and is required during Drosophila dorsal closure and nervous system development. [FBrf0195253]
        Wood et al., 2006, J. Cell Biol. 173(3): 405--416
        Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster. [FBrf0190948]
        Show all research papers ...