Allele Dmel\dpp^TnJMB7

General Information
Symbol	Dmel\dpp^TnJMB7	Species	D. melanogaster
Name		FlyBase ID	FBal0042988
Feature type	allele	Created / Updated	2006-08-20/2006-08-20
Associated gene	Dmel\dpp

Allele class
Mutagen	in vitro construct \| other
Nature of the Allele
Allele class
Mutagen	in vitro construct \| other (Masucci et al., 1990, Staehling-Hampton et al., 1994)
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference Construct: 4kb BamHI fragment from position 106 to 110 is fused at the 3' end of an 8kb fragment of the Hin region (representing the dpp promoter and coding exons) in the same orientation. (Masucci et al., 1990) 4kb fragment within the 3' disk region, the blk enhancer fragment, drives dpp transcription. (Staehling-Hampton et al., 1994)
Assay mode	In transgenic Drosophila (intraspecific) (Staehling-Hampton et al., 1994, Masucci et al., 1990)
Carried in construct	P{TnJMB7} (Staehling-Hampton et al., 1994, Masucci et al., 1990)
Cytology
Phenotypic Data
Phenotypic Class

Phenotype Manifest In

Detailed Description
	Statement Reference
Interactions
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Partially rescues	dpp^TnJMB7 partially rescues dpp^d6 (Masucci et al., 1990)
Fails to rescue	dpp^TnJMB7 fails to rescue dpp^d14/dpp^d12 (Masucci et al., 1990)
Comments	One copy of P{TnJMB7} completely rescues the eye defect of dpp^d6 but only partially rescues leg, antennae, haltere and wing defects. Two copies gives almost complete rescue of all defects and adults are fertile. Two copies fail to rescue defects of class V heterozygote dpp^d12/dpp^d14, individuals fail to form cuticle, most do not eclose from the pupal case, those that do have near full size wings and some legs are missing tarsal segments. (Masucci et al., 1990)
Stocks ( 0 )

Notes on Origin
Discoverer

Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	dpp^TnJMB7
Name Synonym
Secondary FlyBase IDs

References ( 2 )
Research paper	Staehling-Hampton et al., 1994, Cell Growth Diffn 5(6): 585--593 Specificity of bone morphogenetic protein-related factors: Cell fate and gene expression changes in Drosophila embryos induced by decapentaplegic but not 60A. [FBrf0074522] Masucci et al., 1990, Genes Dev. 4(12): 2011--2023 Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements. [FBrf0051842]

Allele Dmel\dppTnJMB7

Allele Dmel\dpp^TnJMB7