A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Dmel\y1

General Information
SymbolDmel\y1SpeciesD. melanogaster
NameFlyBase IDFBal0018607
Feature typealleleCreated / Updated2006-08-22/2006-08-22
Associated geneDmel\y
Allele classamorph, loss of function
Mutagenspontaneous
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Allele class
Mutagen
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      A to C tranversion in the ATG translation initiation codon.
      Deletion of the y promoter, not enhancer.
      Assay mode
      Carried on aberration
       
       
       
      Cytology
      Polytene chromosomes normal.
      hide Phenotypic Data
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      hide Detailed Description
      Statement
      Reference
      Body colour: yellow; hairs & bristles brown with yellow tips; wing veins, wing hairs, yellow. Larval mouth part colour: yellow-brown. Larval denticle belt colour: yellow-brown.
       
      Body colour: no pigmentation.
      The pigmentation induced in unpigmented y1 pharate adult tissue by incubation with dopamine in vitro closely resembles the y1 phenotype, producing brown pigmentation in all cuticle structures.
      Homozygous y+s7 or y2s14 females have a stronger mutant phenotype than y+s7/y1 or y2s14/y1 females in the presence of ph-pP1.
      A stripe of dark pigment seen in wild-type adult females near the posterior edge of abdominal segments A2-A6. I y1 mutants the black melanin is lost from the stripes leaving a brown pigment. The cuticle anterior to the stripe has a tan appearance relative to wild-type. In the thorax and wings, wild-type flies have a uniform colour. In y1 mutants these structures become tan.
      Males have a reduced wing extension index (the percentage of each courtship ritual during which a male's wing is extended and vibrating) compared to wild type.
      y1 males have significantly reduced mating success compared to control males. The Dp(1;f)1187 minichromosome rescues the mating success of these mutants. y1 adults lack pigmentation throughout the body, the wings, bristles, aristae and tarsal claws. The sex combs of y1 males have a lighter colour than wild type.
      Body colour: pigmentation score (where 1 = null/nearly null, 5 = wild type/nearly wild type): homozygote: 1 (wing), 1 (body), hemizygote: 1 (wing), 1 (body), y[1]/y[eve-tata]: 2 (wing), 2-3 (body), y[1]/y[hsp70-tata]: 4-5 (wing), 4[+]-5 (body), y[1]/y[w-DPE26]: 4 (wing), 4 (body), y[1]/y[w-DPE29]: 2 (wing), 1[+]-2 (body), y[1]/y[eve-tata-1]: 1 (wing), 1 (body), y[1]/y[hsp70-tata-1]: 1 (wing), 1 (body), y[1]/y[w-DPE26-1]: 1 (wing), 1 (body), y[1]/y[w-DPE29-1]: 1 (wing), 1 (body), y[1]/y[P1\loxP.eve-700gin]: 2[+]-3 (wing), 2[+] (body), y[1]/y[P1\loxP.hsp70-700gin]: 5 (wing), 4[+]-5 (body), y[1]/y[P1\loxP.w-700gin]: 2[+]-3 (wing), 2[+] (body).
      hide Interactions
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      hideEnhanced by
      Statement
      Reference
      hideNOT Enhanced by
      Statement
      Reference
      hideSuppressed by
      Statement
      Reference
      hideNOT suppressed by
      Statement
      Reference
      hideOther
      Statement
      Reference
      hide Phenotype Manifest In
      hideEnhanced by
      Statement
      Reference
      y1, yEn.GλSλG has cuticle phenotype, enhanceable by su(Hw)unspecified
      y1, yEn.GλSλG has wing phenotype, enhanceable by su(Hw)unspecified
      hideNOT Enhanced by
      Statement
      Reference
      y1, yEn.GλGλS has cuticle phenotype, non-enhanceable by su(Hw)unspecified
      y1, yEn.GλGλS has wing phenotype, non-enhanceable by su(Hw)unspecified
      y1, y2En.2G has cuticle phenotype, non-enhanceable by su(Hw)unspecified
      y1, y2En.2G has wing phenotype, non-enhanceable by su(Hw)unspecified
      y1, y2En.3G has cuticle phenotype, non-enhanceable by su(Hw)unspecified
      y1, y2En.3G has wing phenotype, non-enhanceable by su(Hw)unspecified
      y1, yEn.SλGλG has cuticle phenotype, non-enhanceable by su(Hw)unspecified
      y1, yEn.SλGλG has wing phenotype, non-enhanceable by su(Hw)unspecified
      hideSuppressed by
      Statement
      Reference
      y1, y2En.G has cuticle phenotype, suppressible by su(Hw)unspecified
      hideNOT suppressed by
      Statement
      Reference
      y1, yEn.GλGλS has cuticle phenotype, non-suppressible by su(Hw)unspecified
      y1, yEn.GλGλS has wing phenotype, non-suppressible by su(Hw)unspecified
      y1, y2En.2G has cuticle phenotype, non-suppressible by su(Hw)unspecified
      y1, y2En.2G has wing phenotype, non-suppressible by su(Hw)unspecified
      y1, y2En.3G has cuticle phenotype, non-suppressible by su(Hw)unspecified
      y1, y2En.3G has wing phenotype, non-suppressible by su(Hw)unspecified
      y1, yEn.SλGλG has cuticle phenotype, non-suppressible by su(Hw)unspecified
      y1, yEn.SλGλG has wing phenotype, non-suppressible by su(Hw)unspecified
      y1 has phenotype, non-suppressible by su(Hw)2
      hideSuppressor of
      Statement
      Reference
      y1 is a suppressor of phenotype of svrpoi-Ca
       
      hideOther
      Statement
      Reference
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      A stripe of dark pigment seen in wild-type adult females near the posterior edge of abdominal segments A2-A6. y1, e1 double mutants have brown pigment throughout the abdomen and the stripe is no longer distinct. In the thorax and wings, wild-type flies have a uniform colour. In y1 mutants these structures become tan. In e1 mutants the thorax and wings become more darkly pigmented, and new pigmentation patterns are seen. y1, e1 double mutants also show these patterns, but the black pigment is absent, and they consist of two shades of brown pigment.
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Fails to complement
      Rescued by
      Comments
      hide Stocks ( 13312 )
      Bloomington
      169
      1495
      1496
      1509
      Kyoto
      105766
      101249
      101254
      101257
      106349
      106355
      hide Notes on Origin
      Discoverer
      E.M. Wallace, Jan. 1911.
      hide Comments
      y2 promoter causes trans-activation of enhancer.
      Marker mutation present in the strain used in the genome sequencing project.
      hide Synonyms & Secondary IDs ( 2 )
      Reported As
      Symbol Synonym
      Name Synonym
      Secondary FlyBase IDs
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        hide Recent research papers ( 3 )
        Drapeau et al., 2006, Genetics 172(2): 1009--1030
        A cis-regulatory sequence within the yellow locus of Drosophila melanogaster required for normal male mating success. [FBrf0190716]
        Gilbert et al., 2006, Genetics 173(3): 1365--1375
        The Drosophila boundary element-associated factors BEAF-32A and BEAF-32B affect chromatin structure. [FBrf0192350]
        Lee and Wu, 2006, Genetics 174(4): 1867--1880
        Enhancer-promoter communication at the yellow gene of Drosophila melanogaster: diverse promoters participate in and regulate trans interactions. [FBrf0195007]
        hide Recent reviews (0)
        All reviews listed in FlyBase were published before 2006