Allele Dmel\y1
| General Information | |||
|---|---|---|---|
| Symbol | Dmel\y1 | Species | D. melanogaster |
| Name | FlyBase ID | FBal0018607 | |
| Feature type | allele | Created / Updated | 2006-08-22/2006-08-22 |
| Associated gene | Dmel\y | ||
| Allele class | amorph, loss of function | ||
| Mutagen | spontaneous | ||
Nature of the Allele
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| Allele class | |||
| Mutagen | |||
| Mapped Features and Mutations | |||
Type Symbol & Location Additional Notes References | |||
| Associated Sequence Data | |||
| DDBJ
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EMBL / GenBank | DNA sequence Protein sequence Name | ||
| UniProtKB/Swiss-Prot | |||
| UniProtKB/TrEMBL | |||
| Progenitor genotype | |||
| Nature of the lesion | Statement Reference A to C tranversion in the ATG translation initiation codon. Deletion of the y promoter, not enhancer. | ||
| Assay mode | |||
| Carried on aberration | |||
| Cytology | Polytene chromosomes normal. | ||
Phenotypic Data
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Phenotypic Class
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Phenotype Manifest In
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adult cuticle (with yeve-tata) adult cuticle (with yw-DPE26) adult cuticle (with yw-DPE29) wing (with yeve-tata-1) adult cuticle (with yeve-tata-1) wing (with yhsp70-tata-1) wing (with yw-DPE26-1) adult cuticle (with yw-DPE26-1) wing (with yw-DPE29-1) adult cuticle (with yw-DPE29-1) wing (with yP1\loxP.eve-700gin) wing (with yP1\loxP.w-700gin) | |||
Detailed Description
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Statement Reference Body colour: yellow; hairs & bristles brown with yellow tips; wing veins, wing hairs, yellow. Larval mouth part colour: yellow-brown. Larval denticle belt colour: yellow-brown. Body colour: no pigmentation. A stripe of dark pigment seen in wild-type adult females near the posterior edge of abdominal segments A2-A6. I y1 mutants the black melanin is lost from the stripes leaving a brown pigment. The cuticle anterior to the stripe has a tan appearance relative to wild-type. In the thorax and wings, wild-type flies have a uniform colour. In y1 mutants these structures become tan. Males have a reduced wing extension index (the percentage of each courtship ritual during which a male's wing is extended and vibrating) compared to wild type. y1 males have significantly reduced mating success compared to control males. The Dp(1;f)1187 minichromosome rescues the mating success of these mutants. y1 adults lack pigmentation throughout the body, the wings, bristles, aristae and tarsal claws. The sex combs of y1 males have a lighter colour than wild type. Body colour: pigmentation score (where 1 = null/nearly null, 5 = wild type/nearly wild type): homozygote: 1 (wing), 1 (body), hemizygote: 1 (wing), 1 (body), y[1]/y[eve-tata]: 2 (wing), 2-3 (body), y[1]/y[hsp70-tata]: 4-5 (wing), 4[+]-5 (body), y[1]/y[w-DPE26]: 4 (wing), 4 (body), y[1]/y[w-DPE29]: 2 (wing), 1[+]-2 (body), y[1]/y[eve-tata-1]: 1 (wing), 1 (body), y[1]/y[hsp70-tata-1]: 1 (wing), 1 (body), y[1]/y[w-DPE26-1]: 1 (wing), 1 (body), y[1]/y[w-DPE29-1]: 1 (wing), 1 (body), y[1]/y[P1\loxP.eve-700gin]: 2[+]-3 (wing), 2[+] (body), y[1]/y[P1\loxP.hsp70-700gin]: 5 (wing), 4[+]-5 (body), y[1]/y[P1\loxP.w-700gin]: 2[+]-3 (wing), 2[+] (body). | |||
Interactions
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Phenotypic Class
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Enhanced by | |||
Statement Reference | |||
NOT Enhanced by | |||
Statement Reference y1, yP1\loxP.su(Hw)BR-y-AS-C.-900 has body color defective phenotype, non-enhanceable by Df(3R)su(Hw)V/su(Hw)7 y1, yP1\loxP.gyp-gyp has body color defective phenotype, non-enhanceable by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG yP1\loxP.gyp-gyp/y1 has body color defective phenotype, non-enhanceable by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG | |||
Suppressed by | |||
Statement Reference y1, yP1\loxP.2scs'-2scs' has body color defective phenotype, suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG y1, yP1\loxP.scs-2scs' has body color defective phenotype, suppressible | partially by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG y1/yP1\loxP.2scs'-2scs' has body color defective phenotype, suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG yP1\loxP.scs-2scs'/y1 has body color defective phenotype, suppressible | partially by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG | |||
NOT suppressed by | |||
Statement Reference y1, yP1\loxP.su(Hw)BR-y-AS-C.-900 has body color defective phenotype, non-suppressible by Df(3R)su(Hw)V/su(Hw)7 y1, yP1\loxP.gyp-gyp has body color defective phenotype, non-suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG yP1\loxP.gyp-gyp/y1 has body color defective phenotype, non-suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG | |||
Other | |||
Statement Reference | |||
Phenotype Manifest In
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Enhanced by | |||
Statement Reference | |||
NOT Enhanced by | |||
Statement Reference y1, yP1\loxP.gyp-gyp has adult cuticle phenotype, non-enhanceable by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG yP1\loxP.gyp-gyp/y1 has adult cuticle phenotype, non-enhanceable by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG | |||
Suppressed by | |||
Statement Reference y1, yP1\loxP.2scs'-2scs' has adult cuticle phenotype, suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG y1, yP1\loxP.scs-2scs' has adult cuticle phenotype, suppressible | partially by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG y1/yP1\loxP.2scs'-2scs' has adult cuticle phenotype, suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG yP1\loxP.scs-2scs'/y1 has adult cuticle phenotype, suppressible | partially by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG | |||
NOT suppressed by | |||
Statement Reference y1, yP1\loxP.gyp-gyp has adult cuticle phenotype, non-suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG yP1\loxP.gyp-gyp/y1 has adult cuticle phenotype, non-suppressible by BEAF-32BID.Scer\UAS.T:Ivir\HA1,T:SV40\nls2/Scer\GAL4y.PG | |||
Suppressor of | |||
Statement Reference | |||
Other | |||
Statement Reference | |||
Additional Comments
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Genetic Interactions
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Statement Reference A stripe of dark pigment seen in wild-type adult females near the posterior edge of abdominal segments A2-A6. y1, e1 double mutants have brown pigment throughout the abdomen and the stripe is no longer distinct. In the thorax and wings, wild-type flies have a uniform colour. In y1 mutants these structures become tan. In e1 mutants the thorax and wings become more darkly pigmented, and new pigmentation patterns are seen. y1, e1 double mutants also show these patterns, but the black pigment is absent, and they consist of two shades of brown pigment. | |||
Xenogenetic Interactions
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Statement Reference | |||
Complementation & Rescue Data
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| Fails to complement | |||
| Rescued by | |||
| Comments | |||
Stocks
( 13312 ) | |||
| Bloomington | 169 1628 1495 1496 1509 174 | ||
| Kyoto | 105766 101249 101254 101257 106349 106355 | ||
Notes on Origin
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| Discoverer | E.M. Wallace, Jan. 1911. | ||
Comments
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y2 promoter causes trans-activation of enhancer. Marker mutation present in the strain used in the genome sequencing project. | |||
Synonyms & Secondary IDs
( 2 ) | |||
| Reported As | |||
| Symbol Synonym | |||
| Name Synonym | |||
| Secondary FlyBase IDs | |||
References
( 50 ) | |||
| Generate a list of | |||
| List References by type |
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Recent research papers ( 3 ) | |||
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Recent reviews (0)
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| All reviews listed in FlyBase were published before 2006 | |||
Nature of the Allele