Allele Dmel\rn^roe-1

General Information
Symbol	Dmel\rn^roe-1	Species	D. melanogaster
Name		FlyBase ID	FBal0014643
Feature type	allele	Created / Updated	2006-08-22/2006-08-22
Associated gene	Dmel\rn

Allele class	hypomorph
Mutagen	spontaneous
Nature of the Allele
Allele class	hypomorph
Mutagen	spontaneous
Mapped Features and Mutations
Type Symbol & Location Additional Notes References
Associated Sequence Data
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name

UniProtKB/Swiss-Prot
UniProtKB/TrEMBL

Progenitor genotype
Nature of the lesion	Statement Reference
Assay mode
Cytology
Phenotypic Data
Phenotypic Class
	visible (Ma et al., 1996, Cavener et al., 1986)
Phenotype Manifest In
	eye (Ma et al., 1996, Cavener et al., 1986) ommatidium (Cavener et al., 1986)
Detailed Description
	Statement Reference RK1. phenotype stronger over a deletion than homozygous. Produces a slight roughening of the eye owing to the irregular disposition of the facets; interommatidial bristles lost from posterior portion of the eye. Extreme expression in mutant/deficiency heterozygotes and more so in deficiency homozygotes; enhanced roughening and posterior loss of ommatidial bristles; in addition the eye is reduced in size and remaining interommatidial bristles are clumped. Rough eye: irregular facets. Acts in dosage sensitive manner. (Cavener et al., 1986) Homozygotes exhibit a small rough eye phenotype. (Ma et al., 1996)
Interactions
	Show the genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Enhancer of
Statement Reference rn^roe-1 is an enhancer of phenotype of gl³ (Ma et al., 1996)
Additional Comments
Genetic Interactions
Statement Reference
Xenogenetic Interactions
Statement Reference
Complementation & Rescue Data
Fails to complement	rn^13-1 (Shilkova et al., 2000)
Comments
Stocks ( 77 )
Bloomington	572 rn^roe-1 p^p 1666 Ki¹ rn^roe-1 p^p 997 Df(3L)AC1, rn^roe-1 p^p/TM3, Sb¹ 1901 Df(3R)MAP11, Ki¹ rn^roe-1 p^p/TM3, Sb¹ 2393 Df(3R)WIN11, Ki¹ rn^roe-1 p^p/TM3, Sb¹ 1317 Df(3L)st-e4, Ki¹ rn^roe-1 p^p/TM6B, Tb¹ 2142 Ki¹ pb²⁵ rn^roe-1 p^p/TM3, Sb¹ 2152 Ki¹ pb³⁵ rn^roe-1 p^p/TM3, Sb¹ 2416 Ki¹ mab¹ rn^roe-1 p^p/TM3, Sb¹
Kyoto	105986 rn^roe-1 p^p 106566 Df(3R)MAP11, Ki¹ rn^roe-1 p^p/TM3, Sb¹ 107306 Df(3R)WIN11, Ki¹ rn^roe-1 p^p/TM3, Sb¹
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Notes on Origin
Discoverer	Markowitz, July 1961.

Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	rn^roe-1 roe¹ (Shilkova et al., 2000, Phippen and Parkhurst, 1999, Ma et al., 1996, Markowitz, 1963, Cavener et al., 1986, Lewis et al., 1980, )
Name Synonym
Secondary FlyBase IDs

References ( 6 )
Research paper	Shilkova et al., 2000, D. I. S. 83: 163--164 A genetical mapping and characterization of a new mutation affecting the rotund and roughened eye genes. [FBrf0135616] Ma et al., 1996, Genetics 142(4): 1199--1213 Identification and characterization of autosomal genes that interact with glass in the developing Drosophila eye. [FBrf0087580] Cavener et al., 1986, Genetics 114: 111--123 A rehabilitation of the genetic map of the 84B-D region in Drosophila melanogaster. [FBrf0044420] Lewis et al., 1980, Genetics 95(2): 367--381 Genetic analysis of the Antennapedia gene complex (ANT-C) and adjacent chromosomal regions of Drosophila melanogaster. [FBrf0034853] Markowitz, 1963, D. I. S. 38: 31 [New mutants report.] [FBrf0063666]
Abstract	Phippen and Parkhurst, 1999, A. Dros. Res. Conf. 40: 461A h-NC13, a RING finger protein that interacts with the Orange domain of Hairy. [FBrf0107106]

Allele Dmel\rnroe-1

Allele Dmel\rn^roe-1