A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Allele Dmel\lab15

General Information
SymbolDmel\lab15SpeciesD. melanogaster
NameFlyBase IDFBal0011528
Feature typealleleCreated / Updated2006-08-22/2006-08-22
Associated geneDmel\lab
Allele classhypomorph
MutagenX ray
hide Nature of the Allele
Allele class
hypomorph
(Merrill et al., 1989, Chouinard and Kaufman, 1991, )
Mutagen
X ray
(Merrill et al., 1989)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      deletion
       
      Insertion of about 600bp.
      (Diederich et al., 1989)
      Assay mode
      Cytology
      Polytene chromosomes normal.
      (Merrill et al., 1989)
      Polytene chromosomes normal.
      (Diederich et al., 1989)
      hide Phenotypic Data
      hide Phenotypic Class
      hide Phenotype Manifest In
      embryonic head
      (Merrill et al., 1989)
      larval salivary gland & embryo
      (Merrill et al., 1989)
      hide Detailed Description
      Statement
      Reference
      Hemizygous animals die at the embryonic/first larval instar border. A variable cuticle phenotype is seen, with the severity of the defects correlating with the degree of failure of head involution. The frontal sac appears collapsed, and the pharynx occupies a more anterior position than normal. The salivary glands are missing.
      (Merrill et al., 1989)
      hide Interactions
      hide Phenotypic Class
      hide Phenotype Manifest In
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Comments
      hide Stocks ( 1 )
      Bloomington
      2095
      lab15 pp/TM3, Sb1
      hide Notes on Origin
      Discoverer
      Diederich.
      R. Diederich.
      hide Synonyms & Secondary IDs ( 3 )
      Reported As
      Symbol Synonym
      lab15
       
      labvd2
      (Diederich et al., 1989, Merrill et al., 1989, )
      VD-2
      (Kaufman et al., 1990)
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 4 )
        Research paper
        Chouinard and Kaufman, 1991, Development 113(4): 1267--1280
        Control of expression of the homeotic labial (lab) locus of Drosophila melanogaster: evidence for both positive and negative autogenous regulation. [FBrf0053767]
        Diederich et al., 1989, Genes Dev. 3: 399--414
        Isolation, structure, and expression of labial, a homeotic gene of the Antennapedia Complex involved in Drosophila head development. [FBrf0049820]
        Merrill et al., 1989, Dev. Biol. 135: 376--391
        A genetic and developmental analysis of mutations in labial, a gene necessary for proper head formation in Drosophila melanogaster. [FBrf0049494]
        Review
        Kaufman et al., 1990, Adv. Genet. 27: 309--362
        Molecular and genetic organization of the Antennapedia gene complex of Drosophila melanogaster. [FBrf0051115]