A Database of Drosophila Genes & Genomes

FB2008_06, released July 3, 2008
 

Allele Dmel\bw1

General Information
SymbolDmel\bw1SpeciesD. melanogaster
NameFlyBase IDFBal0001342
Feature typealleleCreated / Updated2006-05-15/2006-05-15
Associated geneDmel\bw
Allele class
Mutagenspontaneous
hide Nature of the Allele
Allele class
Mutagen
spontaneous
(Dreesen et al., 1988)
Mapped Features and Mutations
Type
Symbol & Location
Additional Notes
References
 
 
 
 
Associated Sequence Data
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Progenitor genotype
      Nature of the lesion
      Statement
      Reference
      Insertion of DNA into the transcription unit.
      (Dreesen et al., 1988)
      Assay mode
      Caused by insertion
      412{}bw1
      (Dreesen et al., 1988, FlyBase Genome Annotators, 2002-2003)
      Carried on aberration
      C(2)EN-vNb
      (Novitski et al., 1981, Dernburg et al., 1996)
      Df(2L)PZ07130-mr5
      (Roote, 2000.6.13)
      CyO-Sbw
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      CyO-vAb
      (FlyBase Curators, 2006-, Lindsley and Zimm, 1992)
      Df(2L)k05007-mr1
      (Roote, 2000.6.13)
      Df(2L)PZ06430-mr3
      (Roote, 2000.6.13)
      Df(2L)PZ06430-mr7
      (Roote, 2000.6.13)
      Df(2R)BSC29
      (Deal-Herr and Cook, 2003.4.2)
      Df(2L)PZ07130-mr7
      (Roote, 2000.6.13)
      Df(2L)PZ07130-mr2
      (Roote, 2000.6.13)
      Df(2L)k05007-rv1
      (Roote, 2000.6.13)
      Df(2R)BSC19
      (Deal-Herr and Cook, 2002.7.15)
      Df(2L)PZ06430-mr5
      (Roote, 2000.6.13)
      Df(2L)PZ07130-mr3
      (Roote, 2000.6.13)
      Df(2L)k05007-mr13
      (Roote, 2000.6.13)
      Df(2L)k05007-mr2
      (Roote, 2000.6.13)
      Byron-bw1
      (Henikoff et al., 1995)
      Df(2L)PZ05271-mr33
      (Roote, 2000.6.13)
      Dp(2;2)Cam3a
      (Roote, 2004.6.24)
      Dp(2;2)Cam3
      (Roote, 2004.6.24)
      CyO-pcb
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      In(2R)AT-4
      (Sage and Csink, 2003)
      C(2R)RM-VK1
       
      Df(2L)PZ06430-mr8
      (Roote, 2000.6.13)
      Dp(2;2)Cam17
      (Roote, 2004.6.24)
      Df(2L)PZ06430-mr12
      (Roote, 2000.6.13)
      C(2R)RM-LS1
       
      C(2R)RM-SKIA
       
      Df(2L)k05007-mr6
      (Roote, 2000.6.13)
      Dp(2;2)Cam15
      (Roote, 2004.6.24)
      CyO-Rcb(P)
      (Bloomington Drosophila Stock Center, 2001.8.28)
      Dp(2;2)Cam10
      (Roote, 2004.6.24)
      Df(2L)PZ06430-mr1
      (Roote, 2000.6.13)
      C(2R)RM-G1
       
      C(2)EN-vNc
      (Novitski et al., 1981)
      CyO-Rcb
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      C(2R)RM-VK2
       
      Df(2L)k05007-mr3
      (Roote, 2000.6.13)
      Df(2L)k14608-mr23
      (Roote, 2000.6.13)
      Df(2L)k05007-mr9
      (Roote, 2000.6.13)
      Df(2R)BSC3
      (Bogart and Cook, 2000.11.8)
      C(2)EN-vNa
      (Novitski et al., 1981)
      Df(2L)PZ06430-mr9
      (Roote, 2000.6.13)
      Df(2L)PZ06430-mr13
      (Roote, 2000.6.13)
      Dp(2;2)Cam3c
      (Roote, 2004.6.24)
      Df(2R)BSC39
      (Deal-Herr and Cook, 2003.8.29)
      Df(2L)k05007-mr15
      (Roote, 2000.6.13)
      Dp(2;2)Cam16
      (Roote, 2004.6.24)
      Df(2L)PZ06430-mr4
      (Roote, 2000.6.13)
      Df(2L)PZ07130-mr8
      (Roote, 2000.6.13)
      CyO-Rb
      (FlyBase Curators, 2006-, Bloomington Drosophila Stock Center, 2001.8.28)
      Df(2L)PZ06430-mr10
      (Roote, 2000.6.13)
      Cytology
      hide Phenotypic Data
      hide Phenotypic Class
      eye color defective
       
      chemical resistant | dominant | male
      (Campbell and Nash, 2001)
      chemical resistant | male
      (Campbell and Nash, 2001)
      hide Phenotype Manifest In
      pigment cell
       
      pigment granule
      (Phillips et al., 1973)
      hide Detailed Description
      Statement
      Reference
      Eye colour: brown. Eye colour: light brownish wine on emergence, darkening to garnet. Eye colour: white, with cn1. Eye colour: white, with st1. Eye colour: white, with v1.
       
      Malpighian tubule colour: pale yellow. Testes colour: colourless.
      (Beadle, 1937)
      Red pigments lacking. Xanthommatin mostly replaced by dihydroxanthommatin. Pigment granules present but somewhat smaller than in wild type.
      (Phillips et al., 1973)
      Affects the formation of drosopterins and reduces level of ommochrome in the eye.
      (Tearle, 1991)
      Male heterozygous and homozygous bw1 flies have an increased resistance to the anesthetic enflurane compared to wild-type controls, as judged by climbing ability. This effect is true whether enflurane resistance is measured in regular light or red light. bw1 male flies show no increased resistance to the anesthetic halothane compared to wild-type flies when climbing ability is measured in regular light. However, bw1 mutants show increased sensitivity to this anesthetic when climbing ability is measured in red light.
      (Campbell and Nash, 2001)
      hide Interactions
      hide Phenotypic Class
      hideNOT Enhanced by
      Statement
      Reference
      bw1 has chemical resistant | male | dominant phenotype, non-enhanceable by st1
      (Campbell and Nash, 2001)
      hideNOT suppressed by
      Statement
      Reference
      bw1 has chemical resistant | male | dominant phenotype, non-suppressible by st1
      (Campbell and Nash, 2001)
      hideOther
      Statement
      Reference
      In(2LR)Nella, bw1 has eye color defective phenotype
      (Henikoff et al., 1995)
      hide Phenotype Manifest In
      hideNOT suppressed by
      Statement
      Reference
      bw1 has phenotype, non-suppressible by su(Hw)2
      (Lindsley and Grell, 1968)
      hideOther
      Statement
      Reference
      In(2LR)Nella, bw1 has pigment cell phenotype
      (Henikoff et al., 1995)
      hide Additional Comments
      hide Genetic Interactions
      Statement
      Reference
      Eye colour: off-white, with In(2LR)Nella.
      (Henikoff et al., 1995)
      The increased resistance of bw1 homozygous males to enflurane is not enhanced or suppressed by st1/st1. bw1/+, st1/+ males from bw1, st1 homozygous mothers show increased resistance to halothane when tested under red light and a slight increase in this resistance when tested under white light. A maternal effect is necessary for this phenotype as it is not seen in bw1/+, st1/+ males from bw1, st1 homozygous fathers.
      (Campbell and Nash, 2001)
      hide Xenogenetic Interactions
      Statement
      Reference
      hide Complementation & Rescue Data
      Comments
      hide Stocks ( 1054 )
      Bloomington
      245
      bw1
      264
      cn1 bw1
      433
      vg1 bw1
      668
      v1; bw1
      246
      bw1 bsba
      686
      bw1; st1
      Kyoto
      103250
      bw1
      105812
      bw1
      101540
      lt1 bw1
      103252
      cn1 bw1
      105821
      cn1 bw1
      101838
      v1 ; bw1
      hide Notes on Origin
      Discoverer
      hide Comments
      Eye color autonomous when transplanted into wild-type host.
      (Beadle and Ephrussi, 1936)
      Marker mutation present in the strain used in the genome sequencing project.
      (Misra et al., 2002)
      hide Synonyms & Secondary IDs ( 3 )
      Reported As
      Symbol Synonym
      bw
      (Dernburg et al., 1996, Dreesen et al., 1988, Novitski et al., 1981)
      bw1
       
      unnamed
      (Roote, 2004.6.24)
      Name Synonym
      Secondary FlyBase IDs
        hide References ( 26 )
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