Aberration Dmel\Df(3R)Scx2

General Information
Symbol	Dmel\Df(3R)Scx2	Species	D. melanogaster
Name	Deficiency (3R) Sexcombs extra	FlyBase ID	FBab0002647
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	lab << bk1 << pb << stk << bk2 << hat
Sequence coordinates
Deleted segment	84A5--84C2
Duplicated segment
Computed Breakpoints include	84A5;84C1-84C2
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor	Scr^W (Hazelrigg and Kaufman, 1983) In(3R)Scr^W (Scott et al., 1983)
Mutagen	X ray (Scott et al., 1983, Hazelrigg and Kaufman, 1983)
Class of aberration (relative to progenitor)	chromosomal_deletion (Cavener et al., 1986, Jursnich et al., 1990, Baker et al., 1991, Hazelrigg and Kaufman, 1983)
Breakpoints	84A5;84C1-84C2 (Hazelrigg and Kaufman, 1983) 84B1-84B2;84C1-84C2 (Cavener et al., 1986, Jursnich et al., 1990) 84A5;84B6 (Baker et al., 1991)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments	Distal (84C1-2) breakpoint located at about +41 kb (Baker and Wolfner, 1988, Genes Dev. 2: 477-89); 0 point = HindIII site in αTub84B, '+' values to the right, '-' values to the left).
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0039462) Right limit of break 1 from inclusion of Dfd (FBrf0039462) Left limit of break 2 from inclusion of stk (FBrf0044420) Right limit of break 2 from polytene analysis (FBrf0039462)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Alh (Perrin and Dura, 2004) Mlp84B (Perrin and Dura, 2004) Dfd (Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990, Long et al., 1996) ftz (Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990, Long et al., 1996) αTub84B (Wakimoto et al., 1984, Raff, 1984, Cavener et al., 1986, Matthews and Kaufman, 1987, Hays et al., 1989, Kaufman et al., 1990) Antp (Scott et al., 1983, Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990, Long et al., 1996) Scr (Scott et al., 1983, Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990, Long et al., 1996) bcd (Kaufman et al., 1990, Long et al., 1996) zen (Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990, Long et al., 1996) pb (Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990, Long et al., 1996) l(3)84Bc (Cavener et al., 1986) stk (Cavener et al., 1986, Kaufman et al., 1990) mab (Cavener et al., 1986, Kaufman et al., 1990, Long et al., 1996) l(3)84Bb (Cavener et al., 1986, Kaufman et al., 1990)
Molecular Data
Completely deleted	Alh (Perrin and Dura, 2004)
Genes NOT Deleted / Disrupted
Complementation Data
	αTub84D (Matthews and Kaufman, 1987) sas (Cavener et al., 1986) Gld (Cavener et al., 1986) Taf1 (Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990) dsx (Wakimoto et al., 1984) lab (Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990) twr (Hazelrigg and Kaufman, 1983, Wakimoto et al., 1984, Kaufman et al., 1990) rue (Cavener et al., 1986) l(3)84Ce (Cavener et al., 1986) ted (Cavener et al., 1986) Tpl (Wakimoto et al., 1984) Est-C (Cavener et al., 1986) hat (Cavener et al., 1986) l(3)84Cb (Cavener et al., 1986) gfzf (Cavener et al., 1986) rn (Wakimoto et al., 1984, Cavener et al., 1986)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments
	Does not affect either the "roe" (roughened eye) or "rn" (rotund) functions of the rn locus. (Cavener et al., 1986, Wakimoto et al., 1984) Breakpoint within a 7kb EcoRI fragment just distal to the Alh L isoform transcription start site; the deficiency extends in the proximal direction, completely removing the Alh locus. (Perrin and Dura, 2004)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Homozygous lethal. (Scott et al., 1983, ) Revertant for the \'Scx\' phenotype (extra sex combs on the meso- and metathoracic legs). (Hazelrigg and Kaufman, 1983)
Position Effect Variegation Data

Stocks ( 2 )
Bloomington	2006 Df(3R)Scx2, red¹ e¹/TM3, Sb¹; Dp(3;Y)Antp⁺, y⁺
Kyoto	106625 Df(3R)Scx2, red¹ e¹/TM3, Sb¹; Dp(3;Y)Antp⁺, y⁺
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 17 )
Reported As
Symbol Synonym	Df(3R)Antp^ScxW+R2 (Raff, 1984) Df(3R)Antp-Scx Df(3R)scx2 (Perrin et al., 2003) Df(3R)Scx2 Df(3R)Scx² (Provost et al., 2006) Df(3R)scx² (Perrin et al., 2003) Df(3R)Scx^+RX2 (Fuller, 1986) Df(3R)Scx^w+R2 (Perrin and Dura, 2004) Df(3R)Scx^W+R2 (Baker et al., 1991) Df(3R)Scx^W+RX2 (Wakimoto et al., 1984, Hazelrigg and Kaufman, 1983, Scott et al., 1983, Hays et al., 1989, Merrill et al., 1987, Cavener et al., 1986, ) Df(3R)Scx^w+RX2 (Jursnich et al., 1990) Df(3R)Scx^WRX2 (Mlodzik et al., 1988) Df(3R)Scx-W+R2 (Cavener et al., 1986, ) Scr^W+RX2 (Kaufman et al., 1990) Scr^Wrv2 Scx^W+RX2 (Kaufman et al., 1990)
Name Synonym	Deficiency (3R) Sexcombs extra
Secondary FlyBase IDs
	FBal0045052
References ( 23 )

Generate a list of	All references relating to this aberration ( 23 )

List References by type	Research paper ( 19 ) Review ( 2 ) FlyBase analysis ( 1 ) Book ( 1 )
Recent research papers ( 1 )
	Provost et al., 2006, Genetics 172(1): 207--219 Loss-of-function mutations in a glutathione S-transferase suppress the prune-Killer of prune lethal interaction. [FBrf0190760] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2006 Show reviews ...