Aberration Dmel\Df(2L)sc19-6

General Information
Symbol	Dmel\Df(2L)sc19-6	Species	D. melanogaster
Name	Deficiency (2L) scute19	FlyBase ID	FBab0001913
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	Tps1 << bk1 << l(2)24Fa << l(2)25Cf << bk2 << l(2)25Cg
Sequence coordinates
Deleted segment	24F1--25C5
Duplicated segment
Computed Breakpoints include	24F1-24F2;25C5
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor	Tp(1;2)sc¹⁹
Mutagen	X ray
Class of aberration (relative to progenitor)	chromosomal_deletion (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Rodriguez et al., 1996, Semeshin and Szidonya, 1985)
Breakpoints	24F1-24F4;25B10-25C2 (Semeshin and Szidonya, 1985) 24F1-24F2;25C3-25C5 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988, Rodriguez et al., 1996)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Comments on Cytology
	Left limit of break 1 from polytene analysis (FBrf0042240) Right limit of break 1 from polytene analysis (FBrf0047784) Left limit of break 2 from inclusion of Cg25C (FBrf0087676) Right limit of break 2 from polytene analysis (FBrf0047784)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	Cg25C (Rodriguez et al., 1996) dp (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) jet (Koh et al., 2006) l(2)25Ab (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ce (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ba (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bf (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bb (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Su(var)2-8 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cd (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cf (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) slf (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Be (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bg (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ca (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) M(2)25C (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cc (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)24Fc (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bd (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Bc (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)24Fa (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) M(2)24F (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	Tps1 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) ed (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) ft (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) vri (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) nompC (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) tkv (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) mid (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) cl (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Lam (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Hel25E (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) tutl (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) Msp-300 (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) E(var)25F (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Fa (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) M(2)24D (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ef (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)24Dc (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ee (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)24De (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ed (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)24Dd (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Ea (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) l(2)25Cg (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988) dw-24E (Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Sterile and reduced viability. (Szidonya and Reuter, 1988) The Df(2L)sc19-6 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,w^var}2Lt insertion). (Mason et al., 2004)
Position Effect Variegation Data

Stocks ( 2 )
Bloomington	652 Df(2L)sc19-6/SM6b; Dp(2;1)B19, Df(1)y-ac, sc¹ pn¹: ed¹ dp^o2 cl¹
Kyoto	106028 Df(2L)sc19-6/SM6b; Dp(2;1)B19, Df(1)y-ac, sc¹ pn¹: ed¹ dp^o2 cl¹
Notes on Origin
Discoverer
	Selected for loss of y⁺.
Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	Df(2L)sc19-6 (Koh et al., 2006) Df(2L)sc^19-6 (Semeshin and Szidonya, 1985, Szidonya and Reuter, 1988, Szidonya and Reuter, 1988)
Name Synonym	Deficiency (2L) scute19
Secondary FlyBase IDs

References ( 8 )
Research paper	Mason et al., 2004, Genetics 168(3): 1353--1370 A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277] Rodriguez et al., 1996, Genetics 143(2): 929--940 Identification of immune system and responses genes, and novel mutations causing melanotic tumor formation in Drosophila melanogaster. [FBrf0087676] Szidonya and Reuter, 1988, Genet. Res. 51(3): 197--208 Cytogenetic analysis of the echinoid (ed), dumpy (dp) and clot (cl) region in Drosophila melanogaster. [FBrf0048137] Szidonya and Reuter, 1988, D. I. S. 67: 77--79 Cytogenetics of the 24D4-25F2 region of the Drosophila melanogaster 2L chromosome. [FBrf0047784] Semeshin and Szidonya, 1985, D. I. S. 61: 148--154 EM mapping of rearrangements in the 24-25 sections of Drosophila melanogaster 2L chromosomes. [FBrf0042240]
Supplementary material	Koh et al., 2006, Science 312(5781): Supporting online material for "Jetlag resets the Drosophila circadian clock by promoting light-induced degradation of timeless". [FBrf0199181]
FlyBase analysis	FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type. En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
Book	Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster. The Genome of Drosophila melanogaster. [FBrf0066905]