Aberration Dmel\Df(2L)TW158

General Information
Symbol	Dmel\Df(2L)TW158	Species	D. melanogaster
Name	Deficiency (2L) Ted Wright	FlyBase ID	FBab0001647
Feature type	chromosomal_deletion	Created / Updated	2006-08-22/2006-08-22

Formalized genetic data	l(2)37Bi << bk1 << l(2)37CDf << l(2)37Dk << bk2 << ref(2)P
Sequence coordinates
Deleted segment	37B2--37E2
Duplicated segment
Computed Breakpoints include	37B2--8;[] 37B2-37B8;37E2
Breakpoints Inherited
Nature of the Aberration
Cytological Order
Progenitor
Mutagen	X ray (Wright et al., 1976, Wright et al., 1981, Stathakis et al., 1995)
Class of aberration (relative to progenitor)	chromosomal_deletion (Wright et al., 1976, Wright et al., 1981, Pauli et al., 1995, Stern et al., 1990, Palopoli and Wu, 1996, Tavosanis et al., 1997, Zak, 1998)
Breakpoints	37B2-37B8;37E2-37F4 (Wright et al., 1976, Wright et al., 1981, Stern et al., 1990, Pauli et al., 1995, Palopoli and Wu, 1996, Zak, 1998) 37B2--8;[] (Tavosanis et al., 1997)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments	Breakpoint(s) molecularly mapped (Contamine et al., 1989, Rutledge et al., 1992)
Comments on Cytology
	Limits of break 1 from polytene analysis (FBrf0028752) Left limit of break 2 from polytene analysis (FBrf0028752) Right limit of break 2 from non-inclusion of ref(2)P (citation unavailable)
Molecularly Mapped Breakpoints

Sequence Crossreferences
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name
Gene Deletion & Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted	esc (Wright et al., 1976) amd (Wright et al., 1976) brat (Brittnacher and Ganetzky, 1983) Ddc (Wright et al., 1976, Palopoli and Wu, 1996) hk (Wright et al., 1976) γTub37C (Tavosanis et al., 1997, Schnorrer et al., 2002) RanGap (Palopoli and Wu, 1996) swm (Wright et al., 1976, Brittnacher and Ganetzky, 1983, Gay and Contamine, 1993) Top2 (Palopoli and Wu, 1996) l(2)37Db (Wright et al., 1976, Brittnacher and Ganetzky, 1983) NaCP37B (Stern et al., 1990) l(2)37Dk (Wright et al., 1976) l(2)37Ea (Butler et al., 2001) l(2)37Dl (Wright et al., 1976) l(2)37CDa (Wright et al., 1976) l(2)37CDb (Wright et al., 1976) l(2)37De (Wright et al., 1976, Brittnacher and Ganetzky, 1983) l(2)37CDe (Wright et al., 1976) l(2)37Di (Wright et al., 1976, Brittnacher and Ganetzky, 1983) l(2)37Dm (Wright et al., 1976) l(2)37CDd (Wright et al., 1976) l(2)37CDc (Wright et al., 1976) l(2)37CDf (Wright et al., 1976) l(2)37Dc (Wright et al., 1976, Brittnacher and Ganetzky, 1983)
Molecular Data
Genes NOT Deleted / Disrupted
Complementation Data
	amos (Wright et al., 1976, Ganetzky, 1977) tup (Zak, 1998) barr (Butler et al., 2001) Acon (BDGP Project Members, 1994-1999) cul-2 (BDGP Project Members, 1994-1999) pr (Wright et al., 1976, Ganetzky, 1977) CadN (Wright et al., 1976) spi (BDGP Project Members, 1994-1999) crc (Wright et al., 1976, Ganetzky, 1977) l(2)01528 (BDGP Project Members, 1994-1999) l(2)03832a (BDGP Project Members, 1994-1999) lt (Wright et al., 1976, Ganetzky, 1977) l(2)38Ab (Butler et al., 2001) M(2)39F (Wright et al., 1976) Bl (Wright et al., 1976) l(2)37Fc (Butler et al., 2001) M(2)36F (Wright et al., 1976) rdo (Wright et al., 1976)
Molecular Data
Genes Duplicated
Complementation Data
Molecular Data
Genes NOT Duplicated
Complementation Data
Molecular Data
Related Comments

Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations	Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovo^D2. (Pauli et al., 1995) Shows dominant enhancement of dominant haltere phenotype caused by Ubx¹⁹⁵ and Ubx^9.22. (Burnette et al., 1999)
Position Effect Variegation Data

Stocks ( 3 )
Bloomington	3784 Df(2L)TW158, cn¹ bw¹/CyO
Kyoto	107232 Df(2L)TW158, cn¹ bw¹/CyO 101365 CyO, Cy¹ dp^lv1 pr¹ cn² / Df(2L)TW158, cn¹ bw¹
Notes on Origin
Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments
	The Df(2L)TW158 chromosome acts as a dominant weak suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion), but this is a false positive result (the suppressor is not within the bounds of the deficient region) because the region of the deficiency is covered by one or more nonsuppressing deficiencies. (Mason et al., 2004)
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	158 (Ganetzky, 1977) Df(2L)158 (Brittnacher and Ganetzky, 1983, Wright et al., 1981, Wright et al., 1976, Wright et al., 1976, ) Df(2L)TW158 DF(2l)TW158 (Jordan et al., 2006)
Name Synonym	Deficiency (2L) Ted Wright
Secondary FlyBase IDs
	FBab0001564
References ( 29 )

Generate a list of	All references relating to this aberration ( 29 )

List References by type	Research paper ( 26 ) FlyBase analysis ( 1 ) Computer file ( 1 ) Book ( 1 )
Recent research papers ( 1 )
	Jordan et al., 2006, Genetics 174(1): 271--284 Quantitative trait loci for locomotor behavior in Drosophila melanogaster. [FBrf0193517] Show all research papers ...