A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(2L)Sd37

General Information
SymbolDmel\Df(2L)Sd37SpeciesD. melanogaster
NameDeficiency (2L) Segregation distorterFlyBase IDFBab0001557
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data γTub37C << bk1 << l(2)37Dd << l(2)37Fg << bk2 << pr
Sequence coordinates
Deleted segment37D2--38B2
Duplicated segment
Computed Breakpoints include 37D2-37D5;38A6-38B2
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
X ray
 
Class of aberration (relative to progenitor)
chromosomal_deletion
(Stathakis et al., 1995, Ganetzky, 1977, Pentz et al., 1990)
Breakpoints
37D2-37D7;38A6-38B2
(Ganetzky, 1977, Pentz et al., 1990)
37C6-37D1;38A6-38B2
(Stathakis et al., 1995)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
hide Comments on Cytology
Left limit of break 1 from polytene analysis (FBrf0030142) Right limit of break 1 from inclusion of RanGap (FBrf0030142) Limits of break 2 from polytene analysis (FBrf0030142)
 
Ref: FBrf0030142.
(Stathakis et al., 1995)
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
RanGap
(Ganetzky, 1977, Brittnacher and Ganetzky, 1983, Brittnacher and Ganetzky, 1984, Temin, 1991, McLean et al., 1994)
swm
(Brittnacher and Ganetzky, 1983)
scw
(Butler et al., 2001)
fs(2)ltoPP43
(Butler et al., 2001)
l(2)37Db
(Brittnacher and Ganetzky, 1983)
l(2)37De
(Brittnacher and Ganetzky, 1983)
l(2)37Di
(Brittnacher and Ganetzky, 1983)
l(2)37Fe
(Butler et al., 2001)
E(SD)
(Temin, 1991, McLean et al., 1994)
l(2)37Fc
(Butler et al., 2001)
l(2)38ABb
(Butler et al., 2001)
l(2)37Dc
(Brittnacher and Ganetzky, 1983)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
amos
(Ganetzky, 1977, Brittnacher and Ganetzky, 1983)
Catsup
(Stathakis et al., 1995, Wright, 1996)
Dox-A2
(Stathakis et al., 1995, Wright, 1996)
amd
(Stathakis et al., 1995, Wright, 1996)
brat
(Brittnacher and Ganetzky, 1983, Stathakis et al., 1995, Wright, 1996)
l(2)37Cc
(Stathakis et al., 1995, Wright, 1996)
Ddc
(Brittnacher and Ganetzky, 1983, Stathakis et al., 1995, Wright, 1996)
Lim3
(Stathakis et al., 1995, Wright, 1996)
l(2)37Bb
(Stathakis et al., 1995, Wright, 1996)
hk
(Brittnacher and Ganetzky, 1983, Stathakis et al., 1995, Wright, 1996)
γTub37C
(Stathakis et al., 1995, Wright, 1996)
neb
(Butler et al., 2001)
vls
(Butler et al., 2001)
barr
(Butler et al., 2001)
pr
(Ganetzky, 1977, Brittnacher and Ganetzky, 1983, Temin, 1991)
crc
(Ganetzky, 1977, Brittnacher and Ganetzky, 1983)
lt
(Ganetzky, 1977)
tyr1
(Pentz et al., 1990)
cub
(Stathakis et al., 1995, Wright, 1996)
ms(2)38C
(Brittnacher and Ganetzky, 1983)
M(Sd)
(McLean et al., 1994)
E(SD)
(Brittnacher and Ganetzky, 1984)
hkl
(Stathakis et al., 1995, Wright, 1996)
mib2
(Stathakis et al., 1995, Wright, 1996)
Aats-asn
(Stathakis et al., 1995, Wright, 1996)
l(2)37Cb
(Stathakis et al., 1995, Wright, 1996)
l(2)37Cd
(Stathakis et al., 1995, Wright, 1996)
l(2)37Ce
(Stathakis et al., 1995, Wright, 1996)
l(2)37Cg
(Stathakis et al., 1995, Wright, 1996)
rdo
(Brittnacher and Ganetzky, 1983)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
The Df(2L)Sd37 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3\'WP-2,wvar}2Lt insertion).
(Mason et al., 2004)
hide Position Effect Variegation Data
  
hide Stocks ( 2 )
Bloomington
3779
Df(2L)Sd37/SM5
Kyoto
107227
Df(2L)Sd37/SM5
hide Notes on Origin
Discoverer
Induced on: In(2R)NS, In(2R)SD5, SD-5.
 
Induced: on SD-5.
(Brittnacher and Ganetzky, 1984)
Induced on: SD-5.
(Temin, 1991)
Induced on: SD-5.
(McLean et al., 1994)
Induced on: an SD-5 chromosome carrying In(2R)SD5 and In(2R)NS.
(Ganetzky, 1977)
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      37C6-37D1 breakpoint is between position +60.1 and +66.8 on the Ddc map relative to the HpaI restriction site near the 3' end of Ddc.
      (Stathakis et al., 1995)
      hide Synonyms & Secondary IDs ( 5 )
      Reported As
      Symbol Synonym
      Df(2L)Sd37
       
      Df(2L)Sd37
      (Pentz et al., 1990)
      SD-5R37
      (Brittnacher and Ganetzky, 1983, McLean et al., 1994, Temin, 1991, Brittnacher and Ganetzky, 1984)
      SDRev-37
      (Ganetzky, 1977)
      Name Synonym
      Deficiency (2L) Segregation distorter
       
      Secondary FlyBase IDs
        hide References ( 14 )
        Research paper
        Mason et al., 2004, Genetics 168(3): 1353--1370
        A deficiency screen for dominant suppressors of telomeric silencing in Drosophila. [FBrf0180277]
        De Luca et al., 2003, Nature Genetics 34(4): 429--433
        Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. [FBrf0162261]
        Butler et al., 2001, Genetics 158(4): 1597--1614
        Map position and expression of the genes in the 38 region of Drosophila. [FBrf0138405]
        Wright, 1996, J. Hered. 87(3): 175--190
        The Wilhelmine E. Key 1992 Invitational lecture. Phenotypic analysis of the Dopa decarboxylase gene cluster mutants in Drosophila melanogaster. [FBrf0089206]
        Stathakis et al., 1995, Genetics 141(2): 629--655
        The genetic and molecular organization of the Dopa decarboxylase gene cluster of Drosophila melanogaster. [FBrf0084402]
        McLean et al., 1994, Genetics 137(1): 201--209
        Functional identification of the Segregation distorter locus of Drosophila melanogaster by germline transformation. [FBrf0076533]
        Gay and Contamine, 1993, Molec. gen. Genet. 239(3): 361--370
        Study of the ref(2)P locus of Drosophila melanogaster. [FBrf0059083]
        Temin, 1991, Genetics 128: 339--356
        The independent distorting ability of the Enhancer of Segregation Distortion, E(SD), in Drosophila melanogaster. [FBrf0054143]
        Pentz et al., 1990, Biochem. Genet. 28(3/4): 151--171
        Mutations affecting phenol oxidase activity in Drosophila: quicksilver and tyrosinase-1. [FBrf0051216]
        Brittnacher and Ganetzky, 1984, Genetics 107: 423--434
        On the components of Segregation Distortion in Drosophila melanogaster. [FBrf0040953]
        Brittnacher and Ganetzky, 1983, Genetics 103: 659--673
        On the components of Segregation Distortion in Drosophila melanogaster. [FBrf0039473]
        Ganetzky, 1977, Genetics 86: 321--355
        On the components of Segregation Distortion in Drosophila melanogaster. [FBrf0030142]
        FlyBase analysis
        FlyBase, 2007, En masse symbol-based assigment of Aberration Class with respect to wild type.
        En masse symbol-based assigment of Aberration Class with respect to wild type. [FBrf0191808]
        Book
        Lindsley and Zimm, 1992, The Genome of Drosophila melanogaster.
        The Genome of Drosophila melanogaster. [FBrf0066905]