A Database of Drosophila Genes & Genomes

FB2008_07, released August 8, 2008
 

Aberration Dmel\Df(1)RA2

General Information
SymbolDmel\Df(1)RA2SpeciesD. melanogaster
NameFlyBase IDFBab0000663
Feature typechromosomal_deletionCreated / Updated2006-08-22/2006-08-22
Formalized genetic data l(1)ESHS36 << bk1 << eggroll << l(1)7Do << bk2 << rdgA
Sequence coordinates
Deleted segment7D18--8A4
Duplicated segment
Computed Breakpoints include 7D18-7D22;8A4
Breakpoints Inherited  
hide Nature of the Aberration
Cytological Order
Progenitor
Mutagen
X ray
 
Class of aberration (relative to progenitor)
chromosomal_deletion
(Prudhommeau and Proust, 1990, Dorer et al., 1993, Deak et al., 1982, Bieber et al., 1989, Pauli et al., 1995, Duffy et al., 1996, Silva et al., 1991, Lineruth et al., 1985, King et al., 1986, Ayyub et al., 1990, Harbecke and Lengyel, 1995, Anand and Chandra, 1994, Min and Benzer, 1997, Craymer and Roy, 1980, Porsch et al., 1998)
Breakpoints
7D10;8A4-8A5
(Craymer and Roy, 1980, Deak et al., 1982, Lineruth et al., 1985, King et al., 1986, Bieber et al., 1989, Ayyub et al., 1990, Silva et al., 1991, Anand and Chandra, 1994, Pauli et al., 1995, Harbecke and Lengyel, 1995, Duffy et al., 1996)
7D8;8A5
(Prudhommeau and Proust, 1990)
7D18-7D22;8A4-8A5
(Dorer et al., 1993, Porsch et al., 1998)
7D10;8A4
(Min and Benzer, 1997)
Causes alleles
Carries alleles
Transposon Insertions
Genetic mapping information
Comments
Breakpoint(s) molecularly mapped
(Stewart and Denell, 1993)
hide Comments on Cytology
Left limit of break 1 from polytene analysis (FBrf0058587) Right limit of break 1 from inclusion of l(1)7Dm (FBrf0105246) Left limit of break 2 from polytene analysis (FBrf0034402) Right limit of break 2 from polytene analysis (FBrf0099402)
 
hide Molecularly Mapped Breakpoints
 
hide Sequence Crossreferences
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
hide Gene Deletion & Duplication Data
hide Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
fs(1)h
(Schalet, 1986)
Smox
(Zheng et al., 2003)
Nrg
(King et al., 1986, Bieber et al., 1989)
otu
(Geyer et al., 1993, Pauli et al., 1993)
oc
(Craymer and Roy, 1980, Tearle and Nusslein-Volhard, 1987, Harbecke and Lengyel, 1995, van den Dries et al., 1996)
pt
(King et al., 1986)
gg
(Craymer and Roy, 1980)
l(1)L60.6
(Proust et al., 1992)
l(1)A36.3
(Proust et al., 1992)
lawc
(Zorin et al., 1999)
ibx
(Kerr et al., 1997)
l(1)ESHS39
(Eeken et al., 1985)
l(1)7Di
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)7Dh
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)ESHS32
(Eeken et al., 1985)
l(1)7Dj
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)7Dm
(Henderson and Andrew, 1998)
Is
(Dorer et al., 1993)
l(1)ESHS38
(Eeken et al., 1985)
l(1)7Fg
(Eeken et al., 1985)
ptg
(Craymer and Roy, 1980)
l(1)7Dg
(Zheng et al., 2003)
lix
(Silva et al., 1991)
l(1)7Dk
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)7Do
(Eeken et al., 1985)
eggroll
(Min and Benzer, 1997)
l(1)7Dl
(Henderson and Andrew, 1998, Zheng et al., 2003)
sdt
(Tearle and Nusslein-Volhard, 1987, Harbecke and Lengyel, 1995)
Molecular Data
hide Genes NOT Deleted / Disrupted
Complementation Data
ct
(Eeken et al., 1985, Proust et al., 1992)
sn
(Eeken et al., 1985, Henderson and Andrew, 1998, Zheng et al., 2003)
mys
(Henderson and Andrew, 1998, Zheng et al., 2003)
fs(1)h
(Eeken et al., 1985, Florence and McGinnis, 1998, Zheng et al., 2003)
sesB
(Rikhy et al., 2003)
dec-1
(Lineruth et al., 1985)
txl
(Florence, 1999.7.22)
l(1)D39.5
(Proust et al., 1992)
l(1)7Da
(Schalet, 1986, Henderson and Andrew, 1998)
l(1)7DEa
(Schalet, 1986)
l(1)7Df
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)ESHS31
(Eeken et al., 1985)
l(1)7Dc
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)ESHS36
(Eeken et al., 1985)
l(1)B23.2
(Proust et al., 1992)
l(1)7Dd
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)ESHS29
(Eeken et al., 1985)
l(1)7De
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)ESHS32
(Eeken et al., 1985)
l(1)ESHS34
(Eeken et al., 1985)
l(1)ESHS25
(Eeken et al., 1985)
l(1)ESHS28
(Eeken et al., 1985)
l(1)ESHS33
(Eeken et al., 1985)
l(1)ESHS24
(Eeken et al., 1985)
l(1)ESHS37
(Eeken et al., 1985)
fs(1)M122
(Henderson and Andrew, 1998, Zheng et al., 2003)
l(1)ESHS30
(Eeken et al., 1985)
l(1)ESHS26
(Eeken et al., 1985)
l(1)ESHS35
(Eeken et al., 1985)
l(1)ESHS27
(Eeken et al., 1985)
rdgA
(Harris and Stark, 1977)
Molecular Data
hide Genes Duplicated
Complementation Data
Molecular Data
hide Genes NOT Duplicated
Complementation Data
Molecular Data
hide Related Comments
hide Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations
Deficient embryos show an uninterpretable mutant midgut phenotype.
(Bilder and Scott, 1995)
Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.
(Coyne et al., 1998)
Dominantly causes tergite defects in less than 50% of run3 heterozygotes.
(Duffy et al., 1996)
Heterozygosity for this deletion enhances the mutant ovarian phenotype of ovoD2.
(Pauli et al., 1995)
Heterozygotes have ocelli placed far back on the head and there is a slight indentation in the cuticle beneath the postvertical bristles.
(Craymer and Roy, 1980)
Homozygous embryos are very abnormal compared to wild-type.
(Harbecke and Lengyel, 1995)
Intermediate second site non-complementing phenotype with zipEbr and zipmhc-c6.1: malformed phenotype penetrance 25-75%.
(Halsell and Kiehart, 1998)
More than six-fold reduction in sex ratio and significant levels of female lethality is observed when in combination with Sxlf1. Female lethality is also reduced when in combination with da1 but restored when in combination with emcML.
(Anand and Chandra, 1994)
Shows no maternal enhancement of dpphr4.
(Nicholls and Gelbart, 1998)
The viability of Sxlf1/Df(1)RA2 female progeny derived from a cross between Df(1)RA2/+ females and Sxlf1/Y males is severely reduced. Viability is recovered if the Sxlf1/Df(1)RA2 female progeny also carry Dp(1;3)sn13a1 or if the Df(1)RA2/+ mothers also carry Dp(1;3)sn13a1.
(Sanchez et al., 1994)
hide Position Effect Variegation Data
  
hide Stocks ( 2 )
Bloomington
950
Df(1)RA2/FM7c
Kyoto
108929
Df(1)RA2/FM7c
hide Notes on Origin
Discoverer
Lefevre.
 
hide Balancer / Genotype Variants of the Aberration
    hide Separable Components
      hide Other Comments
      "7D18--22;8A4--5" was stated as revision. Complements Df(1)Desi-S3.
      (Dorer et al., 1993)
      hide Synonyms & Secondary IDs ( 7 )
      Reported As
      Symbol Synonym
      950
      (Rikhy et al., 2003)
      Df(1)oc-RA2
       
      Df(1)RA
      (Prudhommeau and Proust, 1990)
      Df(1)RA2
      (Crest et al., 2007)
      Df(2L)RA2
      (Tearle and Nusslein-Volhard, 1987)
      Df RA2
      (Proust et al., 1992)
      RA2
      (Sanchez et al., 1994)
      Name Synonym
      Secondary FlyBase IDs
      • FBab0022119
      hide References ( 58 )
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      hide Recent research papers ( 1 )
      Crest et al., 2007, Genetics 175(2): 567--584
      Onset of the DNA replication checkpoint in the early Drosophila embryo. [FBrf0194644]
      Show all research papers ...